Geftib 250mg Tablets

Geftib 250mg Tablet is an oral medication that contains Gefitinib. It is used to treat non-small cell lung cancer with mutations in the epidermal growth factor receptor gene. Gefitinib is a tyrosine kinase inhibitor that works by blocking signals that tell cancer cells to grow.

Uses of Geftib 250mg Tablet:

• Non-small cell lung cancer

How does a Geftib 250mg Tablet work?

EGFR tyrosine kinase is involved in signaling pathways that regulate cell migration, survival and proliferation. Gefitinib is a selective inhibitor of EGFR. Gefitinib blocks this route, and can prevent the growth of cancer cells.

How to Use & Dosage

Take this medicine by mouth with a full glass of water. Follow the directions on the medicine label. It may be taken with or without food. Take your medication on schedule. Do not take it more frequently than prescribed. Do not discontinue use except on advice of your physician. If you have trouble taking the tablets tell your doctor, chemist or other healthcare provider. They can counsel you.

Discuss use of this medicine in children with your pediatrician. may need to be extra careful.

250mg once daily, with or without food. Swallow the tablet whole with water. Do not break or chew the tablet.

Possible Side Effects:

• Rash (acne-like)
• Diarrhea
• Fatigue
• Nausea
• Vomiting
• Shortness of breath
• Bone pain
• Constipation
• Loss of appetite
• Dry skin
• Cough

Safety Advise:

🩺 Kidney

People already known to have kidney disease should have regular tests to see how well the kidneys are working. Consult your healthcare professional.

🩸 Liver

Gefitinib may cause liver damage and increase liver enzymes. Liver function tests are recommended on a regular basis, particularly in those with pre-existing liver disease. Please speak with your healthcare provider.

🤰 Pregnancy

Gefitinib use in pregnancy may harm the developing fetus. Effective contraception should be used during treatment. Please discuss with your doctor.

🤱 Breastfeeding

It is not known if erlotinib passes into breast milk. You should not breast-feed while you are receiving this medicine. Please consult your healthcare provider.

🍷 Alcohol

It is not known whether Geftib 250mg Tablet is safe in combination with alcohol. Speak with your doctor.

Storage Instructions:

Store in a dry place at room temperature (15°C to 30°C) and protect from light and humidity.

References

1. Tripathi KD. Essentials of Medical Pharmacology. 8th ed. New Delhi: Jaypee Brothers Medical Publishers.
2. Katzung BG, Vanderah TW. Basic and Clinical Pharmacology. 15th ed. New York: McGraw Hill.
3. Mok TS, Wu YL, Thongprasert S, et al. Gefitinib or carboplatin-paclitaxel in pulmonary adenocarcinoma. New England Journal of Medicine. 2009;361(10):947-957.
4. Ward WH, Cook PN, Slater AM, et al. Epidermal growth factor receptor tyrosine kinase. Investigation of catalytic mechanism, structure-based searching and discovery of a potent inhibitor. Biochemical Pharmacology. 1994;48(4):659-666.
5. AstraZeneca Pharmaceuticals LP. Iressa (gefitinib) Tablets Prescribing Information. Full Prescribing Information, U.S. Food and Drug Administration.

Disclaimer:

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Frequently Asked Questions (FAQs):

What are the uses of Geftib 250mg Tablet?

It is used for treatment of non-small cell lung cancer (NSCLC) especially in patients with EGFR mutation positive tumours.

How does a Geftib 250mg Tablet work?

It contains Gefitinib which blocks the EGFR receptors and slows down the growth and spread of cancer cells.

Geftib is not a chemotherapy medicine.

No, it’s a targeted therapy drug, and it works differently than traditional chemotherapy.

Who can use Geftib Tablet?

It is indicated in patients diagnosed with non-small cell lung cancer, especially those with EGFR mutations.

Is Geftib safe for long-time use?

Yes, it is often used as a long-term treatment, under medical supervision.

Is Geftib good for lung cancer?

Yes. It is used as a targeted therapy of NSCLC and is helping to control the growth of the tumour.

Manufacturer details

Name: Glenmark Pharmaceuticals Ltd.

Address: B/2, Mahalaxmi Chambers,22, Bhulabhai Desai Road, Mumbai – 400026, Maharashtra.

Country of origin: India