5 Fu Gls 500mg Injection

5 Fu Gls 500mg Injection is a cancer medicine containing Fluorouracil. It belongs to the class of drugs known as antimetabolites, which stop cancer cells from growing.

Uses of 5 Fu Gls 500mg Tablet

• Colorectal cancer
• Breast cancer
• Stomach cancer
• Pancreatic cancer
• Head and neck cancers

How does 5 Fu Gls 500mg Tablet work?

Fluorouracil works by blocking the enzyme, thymidylate synthase. This enzyme is required for cells to make DNA. It interferes with the growth and spread of fast growing cancer cells by inserting itself into the DNA and RNA of these cells.

How to Use & Dosage

Given by a doctor through an intravenous (IV) infusion. Dosage and frequency depends on the type of cancer being treated, the health of the patient and other specific circumstances.

Fluorouracil injection comes as a solution to be injected intravenously (into a vein) by a doctor or nurse in a medical facility. How long you will be treated depends on what type of drugs you are taking, how well your body responds to them, and what type of cancer you have.

Your doctor may need to change your dose or delay your treatment if you have some side effects. Tell your doctor how you’re feeling during your fluorouracil injectable treatment, so you can be sure you’re getting the right treatment.

Possible Side Effects

• Nausea
• Vomiting
• Diarrhea
• Mouth sores
• Loss of appetite
• Neutropenia
• Hair loss
• Chest pain
• Hand-foot syndrome
• Redness
• Swelling
• Pain in the palm

Safety Advise

❤️ Heart

Fluorouracil may cause cardiotoxicity and patients with pre-existing heart conditions should be closely monitored. Please check with your healthcare provider.

🩺 Kidney

It is necessary to monitor kidney function tests regularly. Renal Impairment: Dosage adjustments may be required in kidney impairment. Please discuss with your healthcare provider.

🧬 Liver

Liver function tests should be done on a regular basis. Dose adjustment may be required for patients with impaired liver function. Please talk to your doctor.

🤰 Pregnancy

5FU-GLS 500 mg Pregnant women should not receive treatments because they may harm the fetus. Please talk with your health care provider.

🤱 Breastfeeding

It is not known whether it is excreted in human milk. Please see your physician.

Storage Instructions

Store at 15°-25°C (59°-77°F). Do not freeze the solution.

References

• Tripathi KD. Essentials of Medical Pharmacology. 8th ed. New Delhi: Jaypee Brothers Medical Publishers.
• Katzung BG, Vanderah TW. Basic and Clinical Pharmacology. 15th ed. New York: McGraw Hill.
• Longley DB, Harkin DP, Johnston PG. 5-fluorouracil: mechanisms of action and clinical strategies. Nature Reviews Cancer. 2003;3(5):330-338.
• Amstutz U, Henricks LM, Offer SM, et al. Clinical Pharmacogenetics Implementation Consortium (CPIC) guideline for dihydropyrimidine dehydrogenase genotype and fluoropyrimidine dosing. Clinical Pharmacology & Therapeutics. 2018;103(2):210-216.
• Accord Healthcare Inc. Fluorouracil Injection Prescribing Information. Full Prescribing Information, U.S. Food and Drug Administration.

Disclaimer

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