Lentris 4mg Capsule

Lentris 4mg Capsule contains Lenvatinib. Lenvatinib is an oral multi-kinase inhibitor which is mainly used to treat various types of cancer.

Uses of Lentris 4mg Capsule

• Thyroid Cancer
• Endometrial Cancer
• Kidney Cancer
• Liver Cancer

How does Lentris 4mg Capsule work?

Lenvatinib functions by blocking a variety of receptor tyrosine kinases (RTKs), among them the VEGF receptors, which are implicated in angiogenesis, the process of forming new blood vessels which fuels the growth of tumors. It slows the growth and spread of tumors by obstructing these routes.

How to Use & Dosage

Do not break, chew or crush the capsules. Swallow them whole. Take the medicine by mouth with a full glass of water. Read the prescription label carefully, taking it exactly as prescribed by your doctor and stopping only when instructed to do so.

Talk with your paediatrician about using this medicine in children. Extra caution may be needed.

If you think you’ve taken too much of this medication, call an emergency room or poison control centre immediately.

The dosage depends on the type of cancer and the characteristics of the patient (weight, health). The oncologist will prescribe a dose of 4 mg, 8 mg or 12 mg to be taken once a day. Administered orally either with or without food.

Possible Side Effects

• Hypertension
• Diarrhea
• Fatigue
• Nausea
• Vomiting
• Loss of appetite
• Weight loss
• Stomatitis
• Blood Clot
• Headache
• Fever
• Confusion
• Chest Pain

Safety Advise

🫘 Kidney

Caution is advised when using Lentris 4 Capsule in patients with kidney disease. Larger doses of Lentris 4 Capsule may be needed. Talk to your health care provider.

🫀 Liver

Use of Lentris 4 Capsule in patients with liver diseases should be with caution. Lentris 4 Capsule may need dose adjustments. Please see your medical provider.

🤰 Pregnancy

Lentris 4 mg Capsule is not to be consumed during pregnancy as it may be harmful to the foetus. You should not take this medicine during pregnancy. Please see your doctor.

🤱 Breastfeeding

Lenvatinib may be excreted in breast milk. Discuss with your healthcare provider whether you should stop taking the medication or continue breastfeeding.

🍺 Alcohol

The use of alcohol should be avoided when taking Lentris 4mg Capsule as it can increase the risk of experiencing some of the negative effects of the medication. Please consult your health care provider.

Storage Instructions

Store at room temperature, preferably between 20°C and 25°C (68°F and 77°F). Be cautious of extreme cold or freezing conditions.

References

• Tripathi KD. Essentials of Medical Pharmacology. 8th ed. New Delhi: Jaypee Brothers Medical Publishers.
• Katzung BG, Vanderah TW. Basic and Clinical Pharmacology. 15th ed. New York: McGraw Hill.
• Kudo M, Finn RS, Qin S, et al. Lenvatinib versus sorafenib in first-line treatment of patients with unresectable hepatocellular carcinoma. The Lancet. 2018;391(10126):1163-1173.
• Schlumberger M, Tahara M, Wirth LJ, et al. Lenvatinib versus placebo in radioiodine-refractory thyroid cancer. New England Journal of Medicine. 2015;372(7):621-630.
• Eisai Inc. Lenvima (lenvatinib) Capsules Prescribing Information. Full Prescribing Information, U.S. Food and Drug Administration.

Disclaimer

IHS Enterprises’s primary objective is to guarantee the accuracy, reliability, and specialist review of the information it provides to customers. The contents and information provided on this website are for informational purposes only. They should not be used as a substitute for professional medical advice, diagnosis, or treatment. Always consult your physician for guidance and any questions you may have about any condition or medication. If you do read anything from IHS Enterprises, please do not discount or delay in seeking competent medical advice. We want to enhance the doctor-patient relationship, not substitute it.

FAQs (Frequently Asked Questions)

1. What is Lentris 4mg Capsule?

Lentris 4mg is an oral targeted therapy (kinase inhibitor) containing Lenvatinib. It can be prescribed for the treatment of some types of advanced cancers.

2. How could Lenvatinib work?

It is thought to inhibit some receptor tyrosine kinases involved in the growth of tumour blood vessels and the progression of cancer cells. This could potentially slow the growth of the tumour.

3. Conditions it may be prescribed for?

It is approved for: locally recurrent or metastatic thyroid cancer; advanced renal cell carcinoma; and unresectable hepatocellular carcinoma (liver cancer).

4. How to take Lentris 4mg?

It is taken by mouth once a day. Generally, it may be taken with or without food.

5. What is the typical dosage?

The dose you are prescribed will depend on the type of cancer being treated and may involve taking several 4mg or 10mg capsules at one time as directed by your oncologist.

6. What are the side effects?

Possible side effects for patients include high blood pressure, fatigue, diarrhoea, decreased appetite, weight loss or voice hoarseness.

7. Are there any significant cardiovascular risks?

Yes, it can potentially cause severe hypertension, cardiac dysfunction or arterial thromboembolic events (like heart attack or stroke).

8. Do you need to get your blood pressure checked regularly?

Blood pressure is usually closely monitored before and during treatment, as it can often cause significant increases in blood pressure.

9. Can it damage the liver or kidneys?

It can also possibly affect the liver and kidneys, and routine blood tests are needed to monitor these organs.

10. Can I use it during pregnancy?

Lenvatinib may harm an unborn baby and is generally not recommended in pregnancy. You may need effective contraception.

11. What if I throw up after taking a dose?

If vomiting occurs after taking a capsule, it is usually advised not to take another dose and to take the next dose as scheduled the next day.

12. Is Lentris a prescription drug?

Yes, it is a prescription-only oncology drug.

Medical Disclaimer

Lentris 4mg Capsule is a prescription medicine. Take it as prescribed by your doctor. Do not self-medicate, change the dose or discontinue the drug without consulting your doctor. The information on this site is for informational purposes only and is not intended as a substitute for professional medical advice, diagnosis, or treatment. Individual results, benefits and risks will vary. Always speak with your healthcare provider before starting, stopping, or changing any medication.