Aztrohigh 1gm Injection

Aztrohigh 1gm Injection is an antibiotic injection containing Aztreonam, used to treat a wide range of bacterial infections caused by susceptible Gram-negative bacteria. It is effective against infections affecting the urinary tract, lungs, abdomen, skin, soft tissues, bloodstream, and other parts of the body.

Uses of Aztrohigh 1gm Injection:

• Infections caused by susceptible Gram-negative bacteria
• Urinary tract infections
• Respiratory tract infections
• Intra-abdominal infections
• Skin and soft tissue infections

How does Aztrohigh 1gm Injection work?

Aztreonam works by preventing bacteria from forming their protective cell walls. It binds to penicillin-binding proteins (PBPs) in the bacterial cell wall, disrupting cell wall synthesis and causing bacterial cell death. Its unique monobactam structure makes it resistant to many beta-lactamase enzymes produced by resistant Gram-negative bacteria, thereby improving its antibacterial effectiveness.

How to Use & Dosage

Aztrohigh 1gm Injection is administered by a healthcare professional either as an intramuscular (IM) injection or as a slow intravenous (IV) infusion. Before administration, the medicine must be properly reconstituted and diluted according to the manufacturer’s instructions.

If prescribed for home use, you will receive instructions on how to prepare and administer the injection safely. Use the medicine exactly as directed and at the same time each day. Complete the entire course of treatment even if you begin to feel better, unless instructed otherwise by your healthcare provider.

Dispose of used needles and syringes in an approved sharps container. If you suspect an overdose, contact your healthcare provider or visit the nearest emergency department immediately.

Possible Side Effects:

• Nausea
• Vomiting
• Diarrhea
• Rash
• Itching
• Fever
• Fatigue
• Injection site reactions (pain, redness, swelling)
• Allergic reactions (anaphylaxis)
• Elevated liver enzymes

Safety Advice:

🩺 Kidney

Aztrohigh 1gm Injection should be used with caution in patients with kidney disease. Dose adjustments may be required. Please consult your healthcare provider.

🫀 Liver

Patients with liver disease should use Aztrohigh 1gm Injection cautiously. Dose adjustment may be necessary. Please discuss with your healthcare provider before treatment.

🤰 Pregnancy

Use Aztrohigh 1gm Injection during pregnancy only if clearly needed and prescribed by your healthcare provider after carefully evaluating the potential benefits and risks.

🤱 Breastfeeding

Aztreonam passes into breast milk in small amounts. Breastfeeding mothers should consult their healthcare provider before receiving Aztrohigh 1gm Injection.

Storage Instructions

Store at room temperature in a cool, dry place away from moisture and direct sunlight. Keep the medicine in its original packaging until ready for use.

References

1. AZACTAM® (aztreonam for injection, USP). Full Prescribing Information. Princeton, NJ: Bristol-Myers Squibb / Almirall.
2. Romano A, Gaeta F, Valluzzi RL, Alonzi C, Maggioletti M, Zaffiro A, Caruso C. Absence of Cross-Reactivity to Aztreonam in Patients with IgE-Mediated Hypersensitivity to β-Lactam Antibiotics. Journal of Allergy and Clinical Immunology. 2016;138(1):179-186.
3. Zhanel GG, Lawson CD, Adam H, et al. Ceftazidime-Avibactam: A Novel Cephalosporin/β-Lactamase Inhibitor Combination. Drugs. 2013;73(2):159-177.
4. Sykes RB, Bonner DP. Aztreonam: The First Monobactam. American Journal of Medicine. 1985;78(2A):2-10.
5. Brunton LL, Knollmann BC, eds. Goodman & Gilman’s The Pharmacological Basis of Therapeutics. 14th ed. New York: McGraw-Hill Education.

Disclaimer:

IHS Enterprises’s primary objective is to guarantee the accuracy, reliability, and specialist review of the information it provides to customers. The contents and information provided on this website are for informational purposes only. They should not be used as a substitute for professional medical advice, diagnosis, or treatment. Always consult your physician for guidance and any questions you may have about any condition or medication. If you do read anything from IHS Enterprises, please do not discount or delay in seeking competent medical advice. We want to enhance the doctor-patient relationship, not substitute it.

Manufacturer Details

Name: Mankind Pharma Ltd

Address: 208, Okhla Industrial Estate, Phase III, New Delhi – 110020, India.

Country of Origin: India