Altraz 1mg Tablet

Altraz 1mg Tablet contains anastrozole as its active ingredient. It is used in the treatment of breast cancer in women.

Uses of Altraz 1mg Tablet:

• Breast Cancer

How does Altraz 1mg Tablet work?

Anastrozole is an aromatase inhibitor. Aromatase is an enzyme in the body that converts androgens to oestrogens. Anastrozole works by decreasing the amount of oestrogen in the body. Lowering oestrogen levels helps to slow or stop the growth of oestrogen-sensitive tumours.

How to Use & Dosage

1 mg PO daily. Swallow the tablet whole with water, with or without food. Treatment duration depends on the patient’s condition and response to therapy and may last for several years.

Take this medication by mouth with water, as directed on the prescription label. If it causes stomach upset, take it at regular intervals with meals and continue until your doctor tells you to stop.

Ask your child’s doctor about this medicine being used in children. You may have to be extra careful.

Possible Side Effects:

• Hot flashes
• Joint pain
• Fatigue
• Nausea
• Vomiting
• Headache
• Bone thinning
• Heart attack
• Stroke
• Mood changes

Safety Advise:

🦴 Bone

Anastrozole can thin the bones so regular checks on bone density are recommended. You should talk to your doctor.

❤️ Heart

If you have a history of heart disease, your heart health should be monitored carefully as Anastrozole may have an effect on this. Please speak to your health care provider.

🫀 Liver

Liver function tests are often performed routinely in patients with liver disease or symptoms of liver dysfunction. Speak to your health care provider.

🤰 Pregnancy

Anastrozole should not be used during pregnancy as it may cause harm to the foetus. Please consult your health care provider.

🤱 Breastfeeding

Anastrozole is contraindicated in women who are breast-feeding because of the potential for harm to the infant. Please talk to your health care provider.

Storage Instructions:

Store at room temperature (15°-30°C), away from light and moisture. Keep out of children’s reach.

References

• AstraZeneca Pharmaceuticals LP. ARIMIDEX (Anastrozole) Tablets: Highlights of Prescribing Information. U.S. Food and Drug Administration.
• Baum M, Buzdar A, Cuzick J, et al. Anastrozole Alone or in Combination with Tamoxifen versus Tamoxifen Alone for Adjuvant Treatment of Postmenopausal Women with Early-Stage Breast Cancer: Results of the ATAC Trial. The Lancet. 2002;359(9324):2131-2139.
• Buzdar AU, Jonat W, Howell A, et al. Anastrozole versus Megestrol Acetate in the Treatment of Postmenopausal Women with Advanced Breast Cancer. Journal of Clinical Oncology. 1996;14(7):2000-2011.
• Brunton LL, Knollmann BC, eds. Goodman & Gilman’s The Pharmacological Basis of Therapeutics. 14th ed. New York: McGraw-Hill Education.
• Tripathi KD. Essentials of Medical Pharmacology. 8th ed. New Delhi: Jaypee Brothers Medical Publishers.

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