Bevatas 100mg Injection

Bevatas 100mg Injection is a monoclonal antibody used for the treatment of cancer and contains Bevacizumab. It works by blocking angiogenesis, the process by which cancers develop their own blood supply to grow and spread.

Uses of Bevatas 100mg Injection:

• Metastatic Colorectal Cancer
• Non-Small Cell Lung Cancer
• Breast Cancer
• Glioblastoma
• Ovarian Cancer
• Cervical Cancer

How does Bevatas 100mg Injection work?

Bevacizumab targets vascular endothelial growth factor (VEGF), a protein responsible for the formation of new blood vessels. By binding to VEGF, it prevents VEGF from attaching to its receptors on endothelial cells, thereby inhibiting the growth of new blood vessels that tumors require for nourishment and growth. This helps slow tumor progression and reduce the spread of cancer.

How to Use & Dosage

The dosage depends on the type of cancer being treated, the patient’s body weight, and overall health condition. Bevatas 100mg Injection is administered as a slow intravenous (IV) infusion under the supervision of a qualified healthcare professional. The infusion rate may be adjusted based on the patient’s tolerance.

Bevacizumab is generally administered once every 2 to 3 weeks. Your oncologist will determine the appropriate dosage schedule according to your treatment plan.

Serious infusion-related reactions may occur. Seek immediate medical attention if you experience symptoms such as headache, dizziness, chest pain, flushing, itching, skin rash, hives, chills, shivering, sweating, or difficulty breathing during or after the infusion. Your healthcare provider may slow, delay, or discontinue treatment if necessary.

Possible Side Effects:

• Hypertension (high blood pressure)
• Fatigue
• Diarrhea
• Nausea
• Vomiting
• Fever
• Dizziness
• Increased risk of bleeding

Safety Advice:

🫀 Liver

Use with caution in patients with liver impairment. Dose adjustment may be required. Please consult your healthcare provider.

🩺 Kidney

Patients with kidney impairment may require dose adjustment. Kidney function should be monitored during treatment. Please consult your healthcare provider.

🤰 Pregnancy

Bevatas 100mg Injection should be used during pregnancy only if absolutely necessary. It may cause harm to the unborn baby. Effective contraception is recommended during treatment and for the period advised by your doctor.

🤱 Breastfeeding

Breastfeeding is not recommended while receiving Bevatas 100mg Injection and for the duration advised by your doctor after the final dose.

🍷 Alcohol

Avoid consuming alcohol during treatment unless advised otherwise by your healthcare provider.

Storage Instructions:

Store Bevatas 100mg Injection in its original container, protected from light, at a temperature between 2°C and 8°C. Do not freeze. Keep out of the reach of children.

References

1. Genentech, Inc. AVASTIN (Bevacizumab) Injection: Highlights of Prescribing Information. U.S. Food and Drug Administration.
2. Hurwitz H, Fehrenbacher L, Novotny W, et al. Bevacizumab plus Irinotecan, Fluorouracil, and Leucovorin for Metastatic Colorectal Cancer. New England Journal of Medicine. 2004;350(23):2335-2342.
3. Sandler A, Gray R, Perry MC, et al. Paclitaxel-Carboplatin Alone or with Bevacizumab for Non-Small-Cell Lung Cancer. New England Journal of Medicine. 2006;355(24):2542-2550.
4. Brunton LL, Knollmann BC, eds. Goodman & Gilman’s The Pharmacological Basis of Therapeutics. 14th ed. New York: McGraw-Hill Education.
5. Tripathi KD. Essentials of Medical Pharmacology. 8th ed. New Delhi: Jaypee Brothers Medical Publishers.

Disclaimer:

IHS Enterprises’s primary objective is to guarantee the accuracy, reliability, and specialist review of the information it provides to customers. The contents and information provided on this website are for informational purposes only. They should not be used as a substitute for professional medical advice, diagnosis, or treatment. Always consult your physician for guidance and any questions you may have about any condition or medication. If you do read anything from IHS Enterprises, please do not discount or delay in seeking competent medical advice. We want to enhance the doctor-patient relationship, not substitute it.

Frequently Asked Questions (FAQs)

1. What is Bevatas 100mg Injection?

Bevatas 100mg Injection contains Bevacizumab, a targeted monoclonal antibody that inhibits the formation of blood vessels supplying tumors. It is prescribed for the treatment of several advanced cancers under the supervision of an oncologist.

2. How does Bevatas work?

Bevacizumab binds to vascular endothelial growth factor (VEGF), preventing the formation of new blood vessels that tumors require for growth and spread.

3. What cancers is Bevatas used to treat?

It may be prescribed for:

• Metastatic colorectal cancer
• Non-small cell lung cancer
• Glioblastoma
• Ovarian cancer
• Cervical cancer
• Selected cases of breast cancer

4. How is Bevatas administered?

It is administered as an intravenous (IV) infusion by a trained healthcare professional in a hospital or oncology clinic.

5. How often is the infusion given?

The medicine is generally administered once every 2 to 3 weeks depending on the treatment protocol prescribed by your oncologist.

6. What are the common side effects?

Common side effects include high blood pressure, fatigue, diarrhea, nausea, vomiting, headache, dizziness, and nosebleeds.

7. Are there any serious risks?

Yes. Serious complications such as severe bleeding, gastrointestinal perforation, blood clots, delayed wound healing, and infusion-related reactions may occur. Your healthcare team will monitor you closely throughout treatment.

8. Will my blood pressure need monitoring?

Yes. Bevacizumab commonly increases blood pressure, so regular monitoring during treatment is recommended.

9. Does Bevatas affect wound healing?

Yes. It may delay wound healing. Inform your doctor if you have any planned surgery, as treatment may need to be temporarily stopped before and after the procedure.

10. Can Bevatas be used with chemotherapy?

Yes. It is frequently used in combination with chemotherapy regimens depending on the type of cancer and treatment protocol.

11. Can I receive Bevatas during pregnancy?

No. It may cause harm to the developing baby. Effective contraception should be used during treatment and for the period recommended by your healthcare provider after the last dose.

12. Is Bevatas 100mg Injection available only on prescription?

Yes. Bevatas 100mg Injection is a prescription-only medicine and must be administered under the supervision of an oncology specialist.

Medical Disclaimer

Bevatas 100mg Injection is a prescription medicine and should only be used under the supervision of a qualified healthcare professional. Do not self-medicate, alter the dosage, or discontinue treatment without consulting your doctor. The information provided is intended for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Individual responses, benefits, and risks may vary. Always consult your healthcare provider before starting, stopping, or changing any medication.

Manufacturer Details

Name: Intas Pharmaceuticals Ltd

Address: Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad – 380009, Gujarat, India.

Country of Origin: India