CTX-GLS 200mg Injection

CTX-GLS 200mg Injection is an alkylating agent used in chemotherapy. It contains Cyclophosphamide as an active ingredient. Cyclophosphamide is used in the treatment of several types of cancers and some autoimmune diseases.

Uses of CTX-GLS 200mg Injection

• Non-Hodgkin’s and Hodgkin’s lymphomas
• Acute and chronic lymphocytic leukemia
• Multiple Myeloma
• Breast Cancer
• Ovarian Cancer
• Nephrotic Syndrome
• Lung Cancer

How does the CTX-GLS 200mg Injection work?

Cyclophosphamide works by preventing fast dividing cells from replicating their DNA. Cancer cells are fast dividing cells. It cross-links the DNA strands, which stops the cells from proliferating and eventually kills them. Cyclophosphamide can have side effects because it affects healthy cells as well as malignant cells. The effects are most noticeable in tissues with a rapid turnover, such as bone marrow and hair.

How to Use & Dosage

The dose depends on the type of cancer or condition being treated, the body surface area (BSA) of the patient and the overall treatment plan.

This medicine is often given as an infusion into a vein or an injection into a muscle. It is provided in a hospital or clinic by a medical expert with special training.

Please consult a doctor before giving this medicine to a child. It may require additional attention.

Possible Side Effects

• Nausea
• Vomiting
• Infection
• Hair loss
• Fatigue
• Loss of appetite
• Mouth sores

Safety Advise

🫀 Liver

Dose adjustment may be needed in patients with liver disease. You should speak with your health care professional.

🫘 Renal

In patients with kidney disease, dosage adjustments may be needed. Please discuss this with your health care provider.

🤰 Pregnancy

Cyclophosphamide should not be used in pregnancy as it may cause harm to the fetus. Please consult your health care provider.

🤱 Breast Feeding

CTX-GLS 200 mg Nursing mothers should not be given the injection. The drug is known to be potentially harmful to the unborn child. Please consult your healthcare provider.

🍺 Alcohol

Do not consume alcohol while taking CTX-GLS 200mg Injection. Please talk to your health care provider.

Storage Instructions

Store at controlled room temperature 15-30°C (59-86°F). Store in a cool, dry place out of light.

References

• Emadi A, Jones RJ, Brodsky RA. Cyclophosphamide and cancer: golden anniversary. Nature Reviews Clinical Oncology. 2009 Nov;6(11):638-47.
• Bagley Jr CM, Bostick FW, DeVita Jr VT. Clinical pharmacology of cyclophosphamide. Cancer Research. 1973 Feb 1;33(2):226-33.
• Shand FL. The immunopharmacology of cyclophosphamide. International Journal of Immunopharmacology. 1979 Jan 1;1(3):165-71.
• Gamcsik MP, Dolan ME, Andersson BS, Murray D. Mechanisms of resistance to the toxicity of cyclophosphamide. Current Pharmaceutical Design. 1999 Aug 1;5(8):587-605.

Disclaimer

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Manufacturer Details

Name: GLS Pharma Ltd.

Address: R-4, Khirki Main Road, Malviya Nagar, New Delhi – 110017, India

Country of origin: India