Dapmicin 350mg Injection

Dapmicin 350mg Injection contains Daptomycin as an active ingredient. Daptomycin is an antibiotic used to treat serious bacterial infections, particularly those caused by Gram-positive bacteria.

Uses of Dapmicin 350mg Injection:

Severe Bacterial Infection

How does Dapmicin 350mg Injection work?

The cyclic lipopeptide antibiotic daptomycin disrupts cell membranes of Gram-positive bacteria. It binds to the membrane of the bacterial cell and punches holes in it, depolarizing the cell rapidly and causing it to die. This technique is effective against MRSA and other Gram positive resistant bacteria.

How to Use & Dosage?

Dapmicin is a potent drug which requires careful monitoring and is given intravenously, usually in a medical setting. Dose depends on the condition treated, age, weight and renal function of the patient.

Possible Side Effects:

• Nausea
• Vomiting
• Diarrhea
• Constipation
• Pain
• Swelling
• Redness at the injection site
• Headache
• Dizziness
• Muscle Pain
• Weakness

Safety Advise:

Lung

It is not known whether Dapmicin Injection is safe for use in people with lung problems. Please talk to your healthcare provider.

Liver

There is no information on the safety of Dapmicin Injection in people with liver problems. Discuss with your doctor.

Kidney

Dapmicin Injection is unsafe for people with kidney problems. See your healthcare provider.

Pregnancy

Dapmicin should be used during pregnancy only if clearly needed, Please consult your healthcare provider.

Breast Feeding

Dapmicin is probably dangerous to use while breastfeeding. Consult your healthcare provider.

Storage Instructions:

Dapmicin should be kept refrigerated at a temperature between 2°C to 8°C (36°F to 46°F). Freezing should be avoided as freezing could compromise the formulation.

References

1. Heidary M, Khosravi AD, Khoshnood S, Nasiri MJ, Soleimani S, Goudarzi M. Daptomycin. Journal of Antimicrobial Chemotherapy. 2018 Jan 1;73(1):1-1.
2. Enoch DA, Bygott JM, Daly ML, Karas JA. Daptomycin. Journal of Infection. 2007 Sep 1;55(3):205-13.
3. Taylor SD, Palmer M. The action mechanism of daptomycin. Bioorganic & medicinal chemistry. 2016 Dec 15;24(24):6253-68.
4. Tran TT, Munita JM, Arias CA. Mechanisms of drug resistance: daptomycin resistance. Annals of the New York Academy of Sciences. 2015 Sep;1354(1):32-53.

Disclaimer:

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Manufacturer details

Name: Glenmark Pharmaceuticals Ltd
Address: Glenmark Pharmaceuticals Limited, B/2, Mahalaxmi Chambers, 22, Bhulabhai Desai Road, Mumbai – 400 026.
Country of origin: India