Enzamide 40mg Capsule

: Enzamide 40mg Capsule is a medicine which contains Enzalutamide. It is used in the treatment of Prostate Cancer. Your doctor may also prescribe it for other uses. It blocks the action of testosterone and other male hormones.

Uses of Enzamide 40mg Capsule:

• Metastatic castration-resistant prostate cancer.
• Non-metastatic castration-resistant prostate cancer.

How does an Enzamide 40mg Capsule work?

Enzalutamide blocks the androgen receptor. It prevents the action of androgens, such as testosterone, at the receptor site and thus blocks the growth and spread of prostate cancer cells.

How to Use & Dosage

By mouth as a single daily dose. The capsules should be swallowed whole (do not chew or open the capsule) with or without food.

Take this medicine by mouth. Take it at the same time every day as directed on the prescription label. This medication should not be cut, crushed, or chewed. Do not crush or chew the pills. It can be taken with or without food. If it makes you feel sick take it with food. Unless advised otherwise by your healthcare practitioner, continue taking it.

Possible Side Effects:

• Fatigue
• Hot flashes
• Hypertension
• Diarrhea
• Vomiting
• Nausea
• Cough
• Fever
• Rash
• Seizures
• Liver function abnormalities
• Heart failure

Safety Advise:

🫘 Kidney

Enzamide injection should be used with caution in patients with renal disease. The dosage of Enzamide Injection should be changed. Please talk to your health care provider.

🟤 Liver

Patients with severe liver disease taking Enzamide capsules should be carefully monitored. The dose of Enzamide 40mg Capsule may need to be changed. Please talk to your health care provider.

🤰 Pregnancy

This drug is very dangerous. Pregnant women should not take Enzamide injection. Please contact your health care provider.

🤱 Breast Feeding

It is not safe to take Enzamide injection while breast feeding. Please talk to your healthcare provider.

🚗 Driving

It is not known if Enzamide injection affects the ability to drive. Please speak with your healthcare provider.

Storage Instructions:

Store at room temperature in a dry place, protected from heat and out of the reach of children.

References

Astellas Pharma US, Inc./Pfizer Inc. XTANDI (Enzalutamide) Capsules: Highlights of Prescribing Information. U.S. Food and Drug Administration.

Scher HI, Fizazi K, Saad F, et al. Increased Survival with Enzalutamide in Prostate Cancer after Chemotherapy. New England Journal of Medicine. 2012;367(13):1187-1197.

Hussain M, Fizazi K, Saad F, et al. Enzalutamide in Men with Nonmetastatic, Castration-Resistant Prostate Cancer. New England Journal of Medicine. 2018;378(26):2465-2474.

Brunton LL, Knollmann BC, eds. Goodman & Gilman’s The Pharmacological Basis of Therapeutics. 14th ed. New York: McGraw-Hill Education.

Tripathi KD. Essentials of Medical Pharmacology. 8th ed. New Delhi: Jaypee Brothers Medical Publishers.

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