Evermil 10mg Tablet

Evermil 10mg Tablet contains Everolimus which is a drug belonging to the class of drugs called mTOR inhibitors (mammalian target of rapamycin inhibitors). It is primarily used to treat cancer and other diseases.

Uses of Evermil 10mg Tablet:

• Kidney Cancer (Advanced renal cell carcinoma)
• Neuroendocrine tumors of pancreatic origin
• Hormone receptor-positive breast cancer
• Tuberous Sclerosis Complex

How does Evermil 10mg Tablet work?

The mTOR pathway, which is essential for cell division, growth, and survival, is inhibited by everolimus. Everolimus inhibits mTOR, which decreases cell division and limits the growth of cancerous cells.

How to Use & Dosage

The typical dosage is 10 mg once daily, but it can vary based on the specific condition being treated and the patient’s response. Taken orally, with or without food. It is important to take it consistently at the same time each day.

Possible Side Effects:

• Mouth sores
• Nausea
• Diarrhea
• Fatigue
• Rash
• Fever
• Loss of appetite
• Increased risk of infections due to immunosuppression
• Pneumonitis
• Elevated cholesterol and triglycerides

Safety Advise:

Lungs

There have been reports of lung inflammation in patients taking everolimus. Kindly speak with your Healthcare Professional.

Kidney

Creatinine values may rise after taking everolimus, suggesting possible renal impairment. While receiving treatment, patients should have routine renal function testing. Kindly speak with your Healthcare Professional.

Liver

Use of Evermil 10 Tablet is not recommended in patients with severe liver disease. Kindly speak with your Healthcare Professional.

Pregnancy

Everolimus can cause harm to the fetus, leading to birth defects or fetal death. Kindly speak with your Healthcare Professional.

Breast Feeding

Everolimus is not recommended for breastfeeding mothers, as it can pass into breast milk and may harm the nursing infant. Kindly speak with your Healthcare Professional.

Alcohol

It is unknown if drinking alcohol with taking an Evermil 10 Tablet is safe. Kindly speak with your Healthcare Professional.

Driving

Some patients may experience fatigue or dizziness. Be cautious when driving until you know how everolimus affects you.

Storage Instructions

Store at room temperature, away from moisture and heat. Keep out of reach of children.

References

1. Houghton PJ. Everolimus. Clinical cancer research. 2010 Mar 1;16(5):1368-72.
2. Hasskarl J. Everolimus. Small molecules in oncology. 2018:101-23.
3. Kirchner GI, Meier-Wiedenbach I, Manns MP. Clinical pharmacokinetics of everolimus. Clinical pharmacokinetics. 2004 Feb;43:83-95.
4. Yao JC, Shah MH, Ito T, Bohas CL, Wolin EM, Van Cutsem E, Hobday TJ, Okusaka T, Capdevila J, De Vries EG, Tomassetti P. Everolimus for advanced pancreatic neuroendocrine tumors. New England Journal of Medicine. 2011 Feb 10;364(6):514-23.

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Manufacturer details

Name: Glenmark Pharmaceuticals Ltd

Address: Glenmark Pharmaceuticals Limited, B/2, Mahalaxmi Chambers, 22, Bhulabhai Desai Road, Mumbai – 400 026.

Country of origin: India