Magnex Forte 1.5gm Injection

Magnex Forte 1.5gm Injection contains Cefoperazone, Sulbactam it is mainly used for the treatment of different bacterial infections such as Respiratory tract infections, Skin and soft tissue infections, Urinary tract infections and many others.

Uses of Magnex Forte 1.5gm Injection:

• Respiratory tract infections
• Skin and soft tissue infections
• Urinary tract infections
• Gynecological infections
• Bone and joint infections
• Sepsis

How does Magnex Forte 1.5gm Injection work?

The third-generation cephalosporin antibiotic cefoperazone inhibits the formation of the bacterial cell wall, causing cell death. It is often used in combination with sulbactam, a beta-lactamase inhibitor that prevents some resistant bacteria from destroying ceftriaxone. The formulation also contains disodium edetate that is used as a stabiliser that reduces toxicity and increases the general stability of the antibiotic. These elements mutually complement each other and enhance the efficiency of treatment of bacterial infections.

How to Use & Dosage

Administered by a medical professional as an intramuscular (IM) or intravenous (IV) injection. The length of treatment and the dosage depends on the type of infection and the characteristics of the patient.

Possible Side Effects:

• Nausea
• Diarrhea
• Rash
• Pain at the injection site

Safety Advise:

🩺 Kidney

There is inadequate information on the use of Magnex 1.5gm Injection in people with kidney disease. Please talk to your doctor.

🫀 Liver

There is not enough information on the use of Magnex 1.5gm Injection in patients with liver disease. Please talk to your healthcare provider.

🤰 Pregnancy

If pregnant, consult a health care professional. Your doctor should weigh the risks of this medication during pregnancy.

🤱 Breast Feeding

If you are breastfeeding, ask your healthcare professional. Your doctor will need to assess the safety of this medication for you during breast feeding.

🚗 Driving

Drowsiness and lightheadedness, visual disturbances or decreased alertness may occur. If you have these symptoms, don’t drive.

Storage Instructions

Store in a cool, dry place, away from light. Follow exact reconstitution parameters as per manufacturer’s instructions.

References

1. SULPERAZON® (sulbactam sodium/cefoperazone sodium). Full Prescribing Information / Summary of Product Characteristics. New York: Pfizer Inc.
2. MAGNEX® (sulbactam sodium/cefoperazone sodium 1:1) IV/IM. Product Monograph. Mumbai: Pfizer Products India Pvt Ltd.
3. Chen IH, Kuo HY, Lee CH, et al. Clinical Outcomes and Adverse Effects in Septic Patients with Impaired Renal Function Who Received Different Dosages of Cefoperazone–Sulbactam. Infection and Drug Resistance. 2022;15:1863-1874.
4. Yahav D, Mussini C, Leibovici L, Paul M. Cefoperazone/Sulbactam for the Treatment of Serious Bacterial Infections: A Systematic Review and Meta-Analysis. Journal of Antimicrobial Chemotherapy. 2018;73(9):2307-2317.
5. Brunton LL, Knollmann BC, eds. Goodman & Gilman’s The Pharmacological Basis of Therapeutics. 14th ed. New York: McGraw-Hill Education.

Disclaimer:

IHS Enterprises’s primary objective is to guarantee the accuracy, reliability, and specialist review of the information it provides to customers. The contents and information provided on this website are for informational purposes only. They should not be used as a substitute for professional medical advice, diagnosis, or treatment. Always consult your physician for guidance and any questions you may have about any condition or medication. If you do read anything from IHS Enterprises, please do not discount or delay in seeking competent medical advice. We want to enhance the doctor-patient relationship, not substitute it.

Frequently Asked Questions (FAQs):

1. What is Magnex Forte 1.5gm Injection?

Magnex Forte 1.5gm Injection is a combination antibiotic which contains Ampicillin and Sulbactam. It may be prescribed for the treatment of susceptible bacterial infections of the respiratory tract, urinary tract, skin and abdominal region, among others.

2. How does Magnex Forte work?

Ampicillin is a broad-spectrum penicillin antibiotic that can inhibit the synthesis of bacterial cell walls. Sulbactam is a β-lactamase inhibitor that may protect Ampicillin from degradation by certain bacterial resistance enzymes and thus extend its spectrum of activity against resistant organisms.

3. What infections can be treated with Magnex Forte 1.5gm?

Magnex Forte is an antibiotic. It can be used to treat the following bacterial infections:

• Respiratory tract infections caused by susceptible organisms (e.g., pneumonia, bronchitis)
• Infections of the urinary tract
• Soft tissue and skin infections
• Intra-abdominal infections
• Gynaecological infections

The efficacy is contingent on the susceptibility of the infecting organism to this antibiotic combination.

4. How do you take Magnex Forte?

A health care professional gives it as an injection into a vein (intravenous, IV) or a muscle (intramuscular, IM). The amount you will take and how long you will take it will depend on the type and severity of your infection and will be determined by your doctor.

5. What is the usual dose of Magnex Forte?

The usual adult dose is 1.5g (Ampicillin 1g + Sulbactam 0.5g) every 6-8 hours. Based on the severity of renal impairment, dosage adjustment may be required. Follow the regimen prescribed by your doctor.

6. What are the side effects of Magnex Forte?

Possible adverse effects:

• Diarrhoea
• Skin rash
• Nausea
• Injection site reactions
• Elevated liver enzymes

These effects will not occur in all patients. If any side effects are severe or unexpected, tell your doctor immediately.

7. Is Magnex Forte safe for patients allergic to penicillin?

Patients with a known hypersensitivity to penicillins or cephalosporins are at risk for a cross-reactive allergic response. Before starting treatment, it is important to tell your doctor about any drug allergies so that the risk can be assessed correctly.

8. Is it safe to take Magnex Forte in pregnancy?

Your doctor may allow you to use Magnex Forte during pregnancy if the benefits outweigh the potential risk. Always ask your obstetrician before use during pregnancy or lactation.

9. What is the typical length of the treatment course?

Duration of treatment is generally 5 to 14 days, depending on the type and severity of infection and clinical response. It is important to complete the course of antibiotics, even if you feel better, unless your doctor has told you otherwise.

10. Is Magnex Forte a prescription drug?

Yes. It is a prescription only injection antibiotic and must be administered under medical supervision.

Medical Disclaimer

Magnex Forte 1.5gm Injection is a prescription medicine and should only be used under the supervision and guidance of a qualified healthcare professional. Do not self-medicate, change the dose or stop taking it without consulting with your doctor. The information contained herein is for educational purposes only and is not intended to substitute for the advice or treatment of a physician. Results, benefits and risks for each individual may vary. Always check with your doctor before you start, stop or change any medication.

Manufacturer details

Name: Pfizer Ltd

Address: The Capital, 1802, 18th Floor, Plot No. C-70, ‘G’ Block, Bandra Kurla Complex, Bandra East, Mumbai – 400051.

Country of origin: India