Mero SB Injection

Mero SB Injection is a combination of Meropenem and Sulbactam. This antibiotic is used to treat serious bacterial infections such as infections of the skin, abdomen, lungs, and urinary tract. Sulbactam enhances the effectiveness of the wide-spectrum carbapenem antibiotic Meropenem against bacteria that are resistant to it.

Uses of Mero SB Injection:

• Complicated intra-abdominal infections
• Hospital-acquired pneumonia
• Ventilator-associated pneumonia
• Complicated urinary tract infections
• Bloodstream infections (sepsis, bacteremia)
• Skin and soft tissue infections
• Meningitis

How does Mero SB Injection work?

Mero SB Injection contains meropenem, a strong carbapenem antibiotic that kills bacteria by breaking down their cell wall. When used in combination with sulbactam, a β-lactamase inhibitor that prevents bacteria from degrading Meropenem, it is more effective against resistant infections. This combination is used for the treatment of severe bacterial infections by overcoming the antibiotic resistance mechanisms.

How to Use & Dosage

The amount given depends on how serious the infection is and on the condition of the patient. This medication is usually administered through an IV (intravenously) under a doctor’s supervision every 8 hours.

Possible Side Effects:

• Nausea
• Vomiting
• Diarrhea
• Headache
• Injection site pain
• Skin rash

Safety Advise:

🫁 Lungs

Mero-SB Injection may not be safe for people with lung problems. Please speak with your health care team.

🫀 Liver

It is not known if Mero-SB Injection is safe for patients with liver problems. Please speak to your healthcare provider.

🩺 Kidney

Safety of Mero-SB Injection in patients with kidney diseases is unknown. Please discuss this with your healthcare provider.

🤰 Pregnancy

Mero-SB should not be used in pregnancy unless clearly necessary. Please consult your doctor.

🤱 Breast Feeding

Most likely, Mero-SB is not safe to use while breastfeeding. Please consult your healthcare provider.

Storage Instructions

Keep Mero-SB in the refrigerator between 2°C and 8°C (36°F and 46°F). Do not freeze as this may damage the formulation.

References

1. Zhang J, Diao S, Liu Y, Wang H, Liu Y, Zhu S, Feng K, Tang X, Oo C, Zhu P, Lv Z. The combination effect of meropenem/sulbactam/polymyxin-B on the pharmacodynamic parameters for mutant selection windows against carbapenem-resistant Acinetobacter baumannii. Frontiers in Microbiology. 2022 Nov 22;13:1024702.
2. Ko WC, Lee HC, Chiang SR, Yan JJ, Wu JJ, Lu CL, Chuang YC. In vitro and in vivo activity of meropenem and sulbactam against a multidrug-resistant Acinetobacter baumannii strain. Journal of Antimicrobial Chemotherapy. 2004 Feb 1;53(2):393-5.

Disclaimer:

IHS Enterprises’s primary objective is to guarantee the accuracy, reliability, and specialist review of the information it provides to customers. The contents and information provided on this website are for informational purposes only. They should not be used as a substitute for professional medical advice, diagnosis, or treatment. Always consult your physician for guidance and any questions you may have about any condition or medication. If you do read anything from IHS Enterprises, please do not discount or delay in seeking competent medical advice. We want to enhance the doctor-patient relationship, not substitute it.

Frequently Asked Questions (FAQs):

1. What is Mero-SB Injection?

Mero-SB is a combination antibiotic of Meropenem and Sulbactam. It may be prescribed to possibly treat severe, resistant bacterial infections under the supervision of a doctor.

2. How might Mero-SB work?

It is believed Meropenem inhibits bacterial cell wall synthesis and Sulbactam inhibits resistance enzymes (beta-lactamases) to extend the activity of the antibiotic against difficult pathogens.

3. What infections can it be considered for?

As per doctor’s diagnosis, it can be prescribed for serious respiratory tract infections, intra-abdominal infections, septicaemia, and complicated urinary tract infections.

4. How is it administered?

It is given as an intravenous (IV) infusion by a health care professional. You need to follow the infusion schedule that your medical team directs.

5. What about side effects?

Patients may experience possible diarrhoea, nausea, headache or inflammation at the injection site. If they occur, point them out to your doctor.

6. Is it safe in patients allergic to penicillin?

Patients who have a confirmed severe allergy to penicillins or cephalosporins could potentially have a cross-reaction because of the beta-lactam constituents. Tell your doctor about all your allergies.

7. Can it lead to severe diarrhoea?

Like many powerful antibiotics, it can also alter the gut flora, and thus increase the risk of serious intestinal inflammation. If you have severe diarrhoea, follow your doctor’s instructions.

8. Is there a risk of seizures?

Carbapenems like Meropenem may lower the seizure threshold, especially in patients with renal impairment. Never exceed the dosage your doctor prescribes.

9. How long is treatment?

The length of time depends on how severe the infection is. It is very important that you continue to take the medicine for as long as your doctor has told you to, even if you start to feel better.

10. Is routine blood monitoring necessary?

For prolonged courses your doctor may possibly recommend periodic checks of renal and hepatic function. You cannot miss these exams.

11. Can it be used in pediatric patients?

It may be used in children with careful dosage adjustment according to body weight by a pediatrician.

12. Is Mero-SB a prescription drug?

Yes, it is a hospital antibiotic that is available only on prescription.

Medical Disclaimer

Mero-SB Injection is a prescription medicine and must be used only under the direct supervision and guidance of a qualified healthcare professional. Do not change the dose or stop taking it without your doctor’s advice. The information presented here is for educational purposes only and should not be used as a substitute for professional medical advice, diagnosis, or treatment. Results, benefits and risks may vary by individual. Always check with your physician before starting, changing, or discontinuing any medication.

Manufacturer details

Name: Aristo Pharmaceuticals Pvt Ltd

Address: Mercantile Chamber, 3rd Floor, 12, J.N. Heredia Marg, Ballard Estate, Mumbai – 400 001, India.

Country of origin: India