Merrobe 500mg Injection

Merrobe 500mg Injection is a broad spectrum antibiotic that is used to treat serious bacterial infections. It contains meropenem and is used to treat bacterial infections of the skin, soft tissues, blood, brain (meningitis), lungs (pneumonia), urinary tract and many other regions of the body.

Uses of Merrobe 500mg Injection:

• Pneumonia
• Peritonitis and Appendicitis
• Skin and soft tissue infections
• Urinary tract infections (UTIs)
• Meningitis
• Febrile Neutropenia
• Sepsis

How does Merrobe 500mg Injection work?

Meropenem is a carbapenem antibiotic that kills the bacterium by preventing the formation of the bacterial cell wall. It is highly effective against a wide variety of Gram-positive and Gram-negative bacteria, including bacteria that are resistant to other antibiotics.

How to Use & Dosage

Given by injection into a vein. Dosage depends on type and severity of infection, kidney function, and patient age. Administered usually every 8 hours.

This medicine is given through a needle into a vein, usually by a health care professional in a hospital or clinic.

If you will be using this medicine at home, you will be taught how to prepare and give it. Follow the instructions exactly as directed on the prescription label and take it at the same time each day. Keep using it unless your doctor tells you to stop.

Do not throw used needles and syringes in the regular trash. Place them in a special sharps container. If you don’t have one, ask your pharmacist or your health care provider to get you one.

Ask your health care provider about using it in children. It can be prescribed for some conditions in newborns but precautions must be taken.

Possible Side Effects:

• Nausea
• Vomiting
• Diarrhea
• Rash
• Headache
• Allergic reactions
• Seizures
• Thrombocytosis

Safety Advise:

🩺 Kidney

Meropenem is predominantly excreted by the kidney and dose adjustment is necessary in renal impairment. Check with your health care provider.

🫀 Liver

Liver function tests should be performed during prolonged therapy, especially in patients with liver disease, since meropenem may cause elevation of liver enzymes. Check with your health care provider.

🤰 Pregnancy

Meropenem should be used during pregnancy only if clearly needed and only if the potential benefit justifies the potential risk to the fetus. The safety of meropenem during pregnancy has not been established. Please discuss with your healthcare provider.

🤱 Breast Feeding

Use with caution in nursing mothers. The drug may be excreted in breast milk. Talk to your health care professional.

Storage Instructions

Store in a cool dry place away from direct sunlight. Store vials at room temperature prior to reconstitution. The reconstituted solution should be used within the period of stability and efficacy as recommended by the manufacturer.

References

1. Nicolau DP. Pharmacokinetic and pharmacodynamic properties of meropenem. Clinical Infectious Diseases. 2008 Sep 15;47(Supplement_1):S32-40.
2. Edwards JR. Meropenem: a microbiological overview. Journal of Antimicrobial Chemotherapy. 1995 Jul 1;36(suppl_A):1-7.
3. Mouton JW, van den Anker JN. Meropenem clinical pharmacokinetics. Clinical Pharmacokinetics. 1995 Apr;28:275-86.
4. Baldwin CM, Lyseng-Williamson KA, Keam SJ. Meropenem: a review of its use in the treatment of serious bacterial infections. Drugs. 2008 Apr;68:803-38.
5. Craig WA. The pharmacology of meropenem, a new carbapenem antibiotic. Clinical Infectious Diseases. 1997 Feb 1;24(Supplement_2):S266-75.

Disclaimer:

IHS Enterprises’s primary objective is to guarantee the accuracy, reliability, and specialist review of the information it provides to customers. The contents and information provided on this website are for informational purposes only. They should not be used as a substitute for professional medical advice, diagnosis, or treatment. Always consult your physician for guidance and any questions you may have about any condition or medication. If you do read anything from IHS Enterprises, please do not discount or delay in seeking competent medical advice. We want to enhance the doctor-patient relationship, not substitute it.

Frequently Asked Questions (FAQs)

1. What is Merrobe 500mg Injection?

Merrobe 500mg is a broad spectrum carbapenem antibiotic with Meropenem. It may be prescribed for the treatment of serious hospital-acquired bacterial infections. Must comply with hospital physician protocol.

2. What does Meropenem do?

It is thought to prevent formation of the bacterial cell wall, which may result in the rapid death of susceptible bacteria.

3. What infections may it be considered for?

The doctor may prescribe it for complicated intra-abdominal infections, severe pneumonia, complicated urinary tract infections and bacterial meningitis, based on a doctor’s assessment.

4. How is Merrobe 500mg given?

It is given as an intravenous (IV) infusion in a hospital. Your physician has ordered an infusion schedule and rate, which your nursing staff will follow exactly.

5. What is the typical dosage?

A usual dose is 1g every 8 hours but this depends on the severity of infection and kidney function. You have to depend totally on your doctor’s calculated regimen.

6. What side effects can occur?

Patients may experience possible side effects of diarrhoea, nausea, vomiting, headache or reactions at the injection site.

7. Are there serious risks with Meropenem?

Some patients may be at risk of seizures or severe hypersensitivity reactions. The clinical team will monitor you closely to follow safety protocols.

8. Is it safe in penicillin allergic patients?

Low cross-reactivity is possible. Patients that know they are severely allergic to penicillin should inform their doctor to allow an appropriate assessment of risk.

9. Can it cause bad intestinal problems?

It can also alter normal gut bacteria and cause severe diarrhoea (C. difficile infection). Follow your doctor’s advice if you develop persistent diarrhoea.

10. How is it treated?

The duration of treatment depends on the infection and is decided by the treating physician. Even if your symptoms disappear quickly, you still need to complete the full course of treatment.

11. Does it require dose adjustment in kidney issues?

Yes, doses are adjusted in patients with renal impairment. Follow all kidney function monitoring requested by your doctor.

12. Is Merrobe 500mg a prescribed medicine?

Certainly. It is a prescription only injectable antibiotic for use only under medical supervision.

Medical Disclaimer:

Merrobe 500mg Injection is a prescription drug and must be used only under the supervision and direction of a qualified healthcare professional. Do not change your dose or stop taking this medication without your doctor’s advice. The information given here is for educational purposes only and is not a substitute for professional medical advice, diagnosis or treatment. Results, benefits and risks vary by individual. Always check with your doctor before starting, changing or stopping any medication.

Manufacturer details

Name: Glenmark Pharmaceuticals Ltd

Address: Glenmark Pharmaceuticals Limited, B/2, Mahalaxmi Chambers, 22, Bhulabhai Desai Road, Mumbai – 400 026.

Country of origin: India