Pimcef 1gm Injection

Pimcef 1gm Injection is a fourth-generation cephalosporin antibiotic with the active ingredient Cefepime. It is used for the treatment of various bacterial infections. Cefepime works by killing bacteria . It does this by interfering with the formation of bacterial cell walls . It is active against Gram-positive and Gram-negative bacteria, including those resistant to other cephalosporins.

Brand Name: Pimcef

Composition: Cefepime

Mechanism of Action:

Cefepime is a beta-lactam antibiotic that acts on the bacterial cell wall. Its spectrum of activity is wide and includes many Gram-positive and Gram-negative bacteria and some resistant species (Pseudomonas aeruginosa, Enterobacteriaceae). It is more active against bacteria resistant to other cephalosporins because it is stable to most beta-lactamases.

Uses:

• Pneumonia
• Peritonitis and Appendicitis
• Skin and soft tissue infections
• Urinary tract infections (UTIs)
• Meningitis
• Febrile Neutropenia
• Sepsis

Dosage and how to take it:

Routes are intramuscular (IM) or intravenous (IV) injections. The dose of Cefepime is based on the severity of the infection and renal function.

Possible Side Effects:

• Nausea
• Vomiting
• Diarrhea
• Rash
• Headache
• Allergic reactions
• Seizures
• Thrombocytosis

Safety Advise:

Kidney

Cefepime is eliminated mainly by the kidneys and therefore requires dose adjustment in patients with renal impairment. Please check with your health care provider.

Liver

Meropenem may cause raised liver enzymes and prolonged treatment should be monitored by liver function tests particularly in patients with liver disease. Please discuss with your healthcare provider.

Pregnancy

Use cefepime in pregnancy only when clearly needed and under medical supervision, as its safety during pregnancy is not fully determined. Please check with your health care provider.

Breast-Feeding

Breastfeeding Caution should be exercised as the drug may pass into breast milk. Please speak to your healthcare provider.

Driving

It is not known whether Pimcef 1gm Injection affects ability to drive. Please speak with your healthcare provider.

Storage:

Keep in a cool dry place away from sunlight. Store at a temperature below 25°C.

How to use this medication?

Cefepime injection can be given as a premixed medication to be injected into a vein (intravenous) over 30 minutes or as a powder to be mixed with fluids. Cefepime injection can also be injected into a muscle. It is usually given every eight to twelve hours for seven to ten days.

Cefepime may also be given in a hospital or at home by infusion. If you are to receive cefepime at home, your health care professional will instruct you on how to give the injection. Please read these directions carefully and ask your healthcare practitioner if you have any questions.

References:

1. Pacifici GM, Marchini G. Clinical pharmacology of cefepime in infants and children. International Journal of Pediatrics. 2017 Apr 1;5(4):4723-40.
2. Goto A, Amano M, Sakai A, Hara M, Takahashi N. General pharmacology of cefepime. The Japanese Journal of Antibiotics. 1992 Jun 1;45(6):661-80.
3. Barradell LB, Bryson HM. Cefepime: a review of its antibacterial activity, pharmacokinetic properties and therapeutic use. Drugs. 1994 Mar;47:471-505.
4. Okamoto MP, Nakahiro RK, Chin A, Bedikian A. Cefepime clinical pharmacokinetics. Clinical pharmacokinetics. 1993 Aug;25:88-102.

Disclaimer:

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Marketer details:

Name: Venus remedies Limited
Address: SCO 857, 2nd Floor, C. No. 10 NAC Manimajra, Chandigarh, CH 160101
Country of origin: India