Polyfic 500000 Injection

Polyfic 500000 Injection Contains Polymyxin B is an antibiotic used to treat serious bacterial infections caused by Gram-negative bacteria that are resistant to many drugs. It ruptures the bacterial cell membrane, causing the cell to die.

Uses of Polyfic 500000 Injection:

• Severe Bacterial Infections

How does Polyfic 500000 Injection work?

Polymyxin B is a cationic polypeptide antibiotic that interacts with the outer membrane of Gram-negative bacteria and causes damage. This causes lysis of the bacterial cell, leakage of intracellular components and eventual death. Pseudomonas aeruginosa , Acinetobacter baumannii , It mainly targets the Gram-negative multidrug resistant bacteria, Enterobacteriaceae.

How to Use & Dosage

The route of administration can be intramuscular (IM) or intravenous (IV) depending on the clinical situation. adjusted for infection severity and weight. Renal impairment may require dose adjustment.

This medication is administered by a health care professional by injection into a muscle, spinal cord, or vein. It can also be administered in the eye. Sometimes this medicine is used with an irrigation solution to treat the skin. Follow the instructions on the prescription label and those of your health care professional. Never take your medication more frequently than prescribed.

Discuss the use of this drug with your pediatrician for children. You may have to be extra careful.

Possible Side Effects:

• Neurotoxicity
• Nausea
• Vomiting
• Diarrhea
• Dizziness
• Neuromuscular blockade
• Respiratory failure
• Allergic reactions

Safety Advise:

🫁 Lungs

Polyfic isn’t known to be safe for people with lung problems. Talk to your health care professional.

🫀 Liver

It is not known if Polyfic is safe for people with liver problems. Please consult with your healthcare provider.

🩺 Kidney

The safety of Polyfic in people with Kidney problems is not known. Please consult your healthcare provider.

🤰 Pregnancy

If you are pregnant, use Polyfic only if clearly needed. Discuss with your health care provider.

🤱 Breast-Feeding

Using Polyfic while nursing is most likely dangerous. Please speak with your health care provider.

Storage Instructions

Store out of direct sunlight in a dry place below 25°C.

References

1. Avedissian SN, Liu J, Rhodes NJ, Lee A, Pais GM, Hauser AR, Scheetz MH. A review of the clinical pharmacokinetics of polymyxin B. Antibiotics. 2019 Mar 22;8(1):31.
2. Rigatto MH, Falci DR, Zavascki AP. Clinical use of polymyxin B. Polymyxin antibiotics: from laboratory bench to bedside. 2019 Jul 31:197-218.
3. Tam VH, Schilling AN, Vo G, Kabbara S, Kwa AL, Wiederhold NP, Lewis RE. Pharmacodynamics of polymyxin B against Pseudomonas aeruginosa. Antimicrobial agents and chemotherapy. 2005 Sep;49(9):3624-30.

Disclaimer:

IHS Enterprises’s primary objective is to guarantee the accuracy, reliability, and specialist review of the information it provides to customers. The contents and information provided on this website are for informational purposes only. They should not be used as a substitute for professional medical advice, diagnosis, or treatment. Always consult your physician for guidance and any questions you may have about any condition or medication. If you do read anything from IHS Enterprises, please do not discount or delay in seeking competent medical advice. We want to enhance the doctor-patient relationship, not substitute it.

Manufacturer details

Name: Gufic Bioscience Ltd

Address: 37,1st Floor, Kamala Bhavan II, Swami Nityanand Road, Andheri (East), Mumbai – 400 069. (INDIA)

Country of origin: India