Posid 100mg Injection
₹132.00Current price is: ₹132.00.₹181.18 Original price was: ₹181.18.
Brand Name: Posid
Category: Anti Cancer
Manufacturer: Cadila Pharmaceuticals Ltd
Composition: Etoposide
Minimum Order Quantity: 10
1 Vial(s) Of 5ml
Posid 100mg Injection is an injection containing an Etoposide, chemotherapeutic agent used mainly in the treatment of different cancers. It works very well against lung cancer, testicular cancer and some types of leukemia.
Before you take this medicine, tell your doctor if you have any liver or kidney disease or if you have had radiation therapy before. Tell your doctor if you are taking any other medicines, as they may affect how well it works; your doctor may also need to check your blood cells and liver function during treatment.
Product Description
Posid 100mg Injection is an injection containing an Etoposide, chemotherapeutic agent used mainly in the treatment of different cancers. It works very well against lung cancer, testicular cancer and some types of leukemia.
Uses of Posid 100mg Injection:
- Testicular Cancer
- Small Cell Lung Cancer
- Acute Lymphoblastic Leukemia
How does the Posid 100mg Injection work?
Etoposide action involves inhibition of an enzyme (topoisomerase II) which is essential for DNA replication. It blocks the ligation of DNA strands after they are cut, thus causing DNA breaks, and eventually leading to apoptosis (programmed cell death) of cancer cells by stabilizing the topoisomerase II-DNA complex.
How to Use & Dosage
The dosage depends on the exact disease being treated, the general health of the patient and other variables.
Etoposide injection is a solution (liquid) or a powder that is mixed with liquid and then slowly injected into a vein (intravenous) by a doctor or nurse in a medical office. How long your treatment lasts depends on the kind of cancer you have, the medications you take, and how well your body responds to them.
Possible Side Effects:
- Nausea
- Vomiting
- Diarrhea
- Rash
- Headache
- Weakness
- Fever
- Anemia
- Neutropenia
- Difficulty breathing
- Allergic reactions
- Mouth sores
- Constipation
Safety Advise:
🫘 Kidney
Dose adjustments are needed for patients with renal impairment. Please consult your health care provider.
🟤 Liver
Liver function tests should be performed during prolonged treatment, particularly in patients with liver disease, as etoposide can cause elevated liver enzymes. Please talk to your healthcare provider.
🤰 Pregnancy
Etoposide has not been fully established as safe in pregnancy. Etoposide should be used in pregnancy only if clearly needed and under medical supervision. Discuss with your doctor.
🤱 Breast Feeding
A precaution should be taken when breast-feeding as the drug passes into breast milk. Consult with your healthcare provider.
🍷 Alcohol
No information is available on the effects of taking Posid 100mg injection with alcohol. Please talk to your health care provider.
Storage Instructions:
Store in a dry place, protected from light, at room temperature (below 25 °C). Keep out of the reach of children.
References
- Slevin ML. The clinical pharmacology of etoposide. Cancer. 1991 Jan 1;67(S1):319-29.
- Montecucco A, Zanetta F, Biamonti G. Molecular mechanisms of etoposide. EXCLI journal. 2015;14:95.
- Baldwin EL, Osheroff N. Etoposide, topoisomerase II and cancer. Current Medicinal Chemistry-Anti-Cancer Agents. 2005 Jul 1;5(4):363-72.
- Van Maanen JM, Retel J, De Vries J, Pinedo HM. Mechanism of action of antitumor drug etoposide: a review. JNCI: Journal of the National Cancer Institute. 1988 Dec 7;80(19):1526-33.
Disclaimer:
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Manufacturer details:
Name: Cadila Pharmaceuticals Ltd
Address: Sarkhej-Dholka Road, Bhat, Ahmedabad-382 210, INDIA.
Country of origin: India