Tiganex 50mg Injection

Tiganex 50mg Injection is an antibiotic belonging to the glycylcycline class. Tiganex 50mg Injection contains Tigecycline. Tigecycline is a broad spectrum antibiotic used to treat various bacterial infections including resistant infections to other antibiotics.

Uses of Tiganex 50mg Injection:

• Complex infections of the skin and soft tissues
• Complicated intra-abdominal infections
• Community-acquired pneumonia

How does Tiganex 50mg Injection work?

Tigecycline binds to the 30S ribosomal subunit and inhibits bacteria from synthesizing proteins. This effectively halts the growth of bacteria by preventing the addition of amino acids to the growing peptide chain.

How to Use & Dosage

50 mg within 12 hours usually as an IV infusion over 30 to 60 minutes. Duration of treatment (usually 5 to 14 days) is determined on the kind and severity of infection.

Tigecycline injections can be given at home or in a hospital with proper instruction from a health care professional about how to give the medication and how to deal with any problems.

You should start to feel better within the first few days of receiving injectable tigecycline. Call your physician if your symptoms do not improve or get worse.

Possible Side Effects:

• Nausea
• Vomiting
• Diarrhea
• Headache
• Abdominal pain
• Elevated liver enzymes

Safety Advise:

🫀 Liver

Use with caution in patients with Liver dysfunction. In patients with severe liver dysfunction dose adjustment is required. Talk to your doctor.

🩺 Kidney

No dose adjustment is required in patients with renal impairment but patients with severe renal failure should be cautioned. Please consult with your healthcare provider.

🤰 Pregnancy

Tigecycline can harm an unborn baby if the mother takes the drug during pregnancy. Consult your health care professional.

🤱 Breast Feeding

It is not recommended to use it during breast feeding because it may pass into the breast milk and cause harm to your baby. Please consult your healthcare provider.

🚗 Driving

Tigecycline can cause vision problems or dizziness. If these effects occur patients should be cautioned against driving. Please see your healthcare provider.

Storage Instructions

Store at 25°C (77°F); allowable temperature range 15°C to 30°C (59°F to 86°F). Keep the vial in the original packing to protect it from light.

References

1. Pankey GA. Tigecycline. Journal of Antimicrobial Chemotherapy. 2005 Sep 1;56(3):470-80.
2. Livermore DM. Tigecycline: what is it, and where should it be used?. Journal of Antimicrobial Chemotherapy. 2005 Oct 1;56(4):611-4.
3. Stein GE, Babinchak T. Tigecycline: an update. Diagnostic Microbiology and Infectious Disease. 2013 Apr 1;75(4):331-6.
4. Rubinstein E, Vaughan D. Tigecycline: a novel glycylcycline. Drugs. 2005 Jul;65:1317-36.

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Manufacturer details

Name: Cipla Ltd

Address: Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013

Country of origin: India