Xavitaz 2.5gm Injection

Xavitaz 2.5gm Injection is an antibiotic Injection containing Ceftazidime, Avibactam, which is used in the treatment of severe bacterial infections of the stomach, urinary system and lungs. It may be used alone or in conjunction with other antibiotics, such as metronidazole, in adults and children for the treatment of a variety of diseases.

Uses of Xavitaz 2.5gm Injection:

• Urinary tract infections
• Intra-abdominal infections
• Hospital-acquired bacterial pneumonia and ventilator-associated bacterial pneumonia.

How does Xavitaz 2.5gm Injection work?

Ceftazidime is a third-generation cephalosporin antibiotic which inhibits bacterial cell wall formation, resulting in cell lysis and death. Avibactam is a non-beta-lactam beta-lactamase inhibitor that improves the effectiveness of ceftazidime against infections caused by beta-lactamase-producing bacteria by shielding it from degradation by specific enzymes produced by these resistant bacteria.

How to Use & Dosage

Given intravenously, usually over 2 hours. Dosage and duration depend on the type and severity of infection, and patient factors, such as renal function.

This medication is given as an injection into a vein or muscle every 8 to 12 hours; the amount is based on the child’s weight and condition. Check for particles or discoloration before use, and ask your health care professional how to properly prepare and store it. If using a pre-mixed solution that has been frozen, defrost it at room temperature or in the refrigerator and give it a good shake. Use the antibiotic at equal intervals to maximise its effectiveness.

Possible Side Effects:

• Fatigue
• Hot flashes
• Hypertension
• Nausea
• Vomiting
• Allergic reactions (anaphylaxis)
• Renal impairment
• Seizures

Safety Advise:

🩺 Kidney

Xavitaz 2.5gm injection is safe to be used in patients having renal disease. Take Cavim 2.5 mg injection as directed by your doctor.

🤰 Pregnancy

Taking Xavitaz 2.5gm injection during pregnancy is very harmful. Seek counsel from your doctor, as research on pregnant women and animals have indicated considerable risk to the growing infant.

🤱 Breast Feeding

You should not take the Xavitaz 2.5gm injection when breast feeding. The data suggest that the drug could be dangerous for the baby.

Storage Instructions

Store away from direct sunlight in a cool, dry place. After reconstitution, refer to the product literature for specific storage instructions.

References

1. AVYCAZ® (ceftazidime and avibactam) for Injection, for Intravenous Use. Full Prescribing Information. Silver Spring, MD: U.S. Food and Drug Administration.
2. Sharma R, Eun Park T, Moy S. Ceftazidime-Avibactam (Avycaz): For the Treatment of Complicated Intra-Abdominal and Urinary Tract Infections. Pharmacy and Therapeutics. 2016;41(1):11-14.
3. Wagenlehner FM, Sobel JD, Newell P, et al. Ceftazidime-Avibactam Versus Doripenem for the Treatment of Complicated Urinary Tract Infections, Including Acute Pyelonephritis: RECAPTURE, a Phase 3 Randomized Trial Program. Clinical Infectious Diseases. 2016;63(6):754-762.
4. Torres A, Zhong N, Pachl J, et al. Ceftazidime-Avibactam Versus Meropenem in Nosocomial Pneumonia, Including Ventilator-Associated Pneumonia (REPROVE): A Randomised, Double-Blind, Phase 3 Non-Inferiority Trial. The Lancet Infectious Diseases. 2018;18(3):285-295.
5. Brunton LL, Knollmann BC, eds. Goodman & Gilman’s The Pharmacological Basis of Therapeutics. 14th ed. New York: McGraw-Hill Education.

Disclaimer:

IHS Enterprises’s primary objective is to guarantee the accuracy, reliability, and specialist review of the information it provides to customers. The contents and information provided on this website are for informational purposes only. They should not be used as a substitute for professional medical advice, diagnosis, or treatment. Always consult your physician for guidance and any questions you may have about any condition or medication. If you do read anything from IHS Enterprises, please do not discount or delay in seeking competent medical advice. We want to enhance the doctor-patient relationship, not substitute it.