Zoladex 3.6mg Injection

Zoladex 3.6mg Injection contains Goserelin acetate, a synthetic hormone and gonadotropin-releasing hormone (GnRH) analogue.

Uses of Zoladex 3.6mg Injection:

• Prostate Cancer
• Breast Cancer
• Endometriosis
• Uterine Fibroids

How does Zoladex 3.6mg Injection work?

Zoladex works by preventing the pituitary gland from releasing gonadotropins (FSH and LH). This reduces the production of sex hormones (oestrogen in women and testosterone in men), thereby lowering hormone levels and slowing the growth of hormone-dependent conditions.

How to Use & Dosage

Zoladex is normally given as a subcutaneous injection (implant under the skin) every month or every three months, depending on the indication and treatment regimen. It is administered by a qualified healthcare professional.

This medicine uses a small implant that slowly releases Goserelin into the body. The implant is injected under the skin of the lower abdomen, just below the belly button, and is gradually absorbed by the body over several weeks or months.

Use this medicine exactly as prescribed by your doctor. The 3.6mg implant is generally administered every 4 weeks, while the longer-acting formulation is given every 12 to 13 weeks. Follow your doctor’s instructions carefully and do not stop treatment without medical advice.

Possible Side Effects:

• Hot flashes
• Night sweats
• Weight gain
• Mood changes
• Dizziness
• Allergic reactions
• Osteoporosis
• Reduced libido
• Nausea
• Vomiting
• Fever

Safety Advise:

🫁 Lungs

It is not known whether Zoladex Injection is safe for people with lung problems. Please consult your healthcare provider.

🩸 Liver

There is limited information regarding the safety of Zoladex Injection in patients with liver disease. Please consult your healthcare provider.

🩺 Kidney

The safety of Zoladex Injection in people with kidney problems is not well established. Please consult your healthcare provider.

🤰 Pregnancy

Zoladex should only be used during pregnancy if clearly needed. Please consult your healthcare provider.

🤱 Breastfeeding

Breastfeeding while receiving Zoladex is generally not recommended. Please consult your healthcare provider.

Storage Instructions:

Store Zoladex in a refrigerator at 2°C to 8°C. Do not freeze. Freezing may damage the formulation.

References

1. Tripathi KD. Essentials of Medical Pharmacology. 8th ed. New Delhi: Jaypee Brothers Medical Publishers.
2. Katzung BG, Vanderah TW. Basic and Clinical Pharmacology. 15th ed. New York: McGraw Hill.
3. Thompson IM. Flare Associated with LHRH-Agonist Therapy. Reviews in Urology. 2001;3(Suppl 3):S10-S14.
4. TerSera Therapeutics LLC. Zoladex (Goserelin Implant) 3.6mg Prescribing Information. Full Prescribing Information. U.S. Food and Drug Administration.
5. Kumar D, Salian SR, Kalthur G, et al. Association between Tumor Flare and Clinical Outcomes in Patients Treated with GnRH Agonists for Prostate Cancer. Reviews in Urology. 2013;15(1):8-15.

Disclaimer:

IHS Enterprises’s primary objective is to guarantee the accuracy, reliability, and specialist review of the information it provides to customers. The contents and information provided on this website are for informational purposes only. They should not be used as a substitute for professional medical advice, diagnosis, or treatment. Always consult your physician for guidance and any questions you may have about any condition or medication. If you do read anything from IHS Enterprises, please do not discount or delay in seeking competent medical advice. We want to enhance the doctor-patient relationship, not substitute it.

Frequently Asked Questions (FAQs)

1. What is Zoladex 3.6mg Injection?

Zoladex 3.6mg contains the active ingredient Goserelin, which is an LHRH agonist. It is a hormone therapy that may be prescribed for the treatment of prostate cancer or certain gynaecological conditions. It is important to follow the specialist’s treatment protocol strictly.

2. How does Zoladex work?

It initially increases hormone production briefly before suppressing the production of testosterone (in men) or oestrogen (in women), helping control hormone-dependent conditions.

3. What conditions is it used for?

Zoladex 3.6mg may be prescribed for advanced prostate cancer, breast cancer, endometriosis, and uterine fibroids as determined by your healthcare provider.

4. How is Zoladex 3.6mg administered?

It is administered as a subcutaneous implant under the skin of the abdomen by a trained healthcare professional according to the prescribed treatment schedule.

5. How often is the 3.6mg injection given?

The 3.6mg formulation is usually administered once every 4 weeks. Follow your doctor’s schedule carefully and do not miss appointments.

6. What are the possible side effects?

Common side effects include hot flushes, sweating, reduced libido, erectile dysfunction, mood changes, and pain at the injection site.

7. What is a tumour flare?

Hormone levels may temporarily rise during the first few weeks of treatment, which can briefly worsen symptoms before hormone suppression occurs. Your doctor may prescribe additional medication to reduce this effect.

8. Can Zoladex affect bone density?

Long-term hormone suppression may reduce bone density and increase the risk of osteoporosis. Your doctor may recommend bone health monitoring or supportive therapy.

9. Are there cardiovascular or metabolic risks?

Long-term hormonal therapy may increase the risk of diabetes or cardiovascular disease. Regular health monitoring is recommended.

10. What happens if a dose is delayed?

Missing or delaying a scheduled dose may allow hormone levels to increase again, potentially reducing treatment effectiveness. Always follow your doctor’s schedule.

11. How should Zoladex be stored?

Store the medicine in a refrigerator at 2°C to 8°C. If you are handling the package yourself, follow the storage instructions provided by your pharmacist.

12. Is Zoladex a prescription medicine?

Yes. Zoladex is a prescription-only medicine and should be used only under the supervision of a qualified healthcare professional.

Medical Disclaimer

Zoladex 3.6mg Injection is a prescription medication and should only be used under the supervision and guidance of a qualified healthcare professional. Do not self-medicate, change the dose, or discontinue treatment without consulting your doctor. The information provided is intended for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Individual results, benefits, and risks may vary.

Manufacturer Details

Name: AstraZeneca

Address: Corporate & Registered Office, Block N1, 12th Floor, Manyata Embassy Business Park, Rachenahalli, Outer Ring Road, Bangalore – 560045, India.

Country of Origin: India