Letall 2.5mg Tablet

Letall 2.5mg tablets contain Letrozole, an aromatase inhibitor which is used in the treatment of hormone receptor positive breast cancer in postmenopausal women. Letrozole stops the production of estrogen, which some breast cancers need to grow.

Uses of Letall 2.5mg tablet:

• Breast Cancer

How does a Letall 2.5mg tablet work?

Letrozole inhibits the aromatase enzyme, which converts androgens into oestrogen. Letrozole lowers the level of oestrogen to slow or stop the growth of estrogen sensitive breast cancers.

How to Use & Dosage

2.5mg once daily. for food and non-food consumption Suggested to be taken at the same time every day.

Take this prescription with a full glass of water. You can eat or not when you take it. Take as directed on the medicine label. Take your prescribed medicines regularly. Do not take your prescription more often than prescribed. Do not stop taking them unless your care team tells you to.

Discuss the use of this drug in children with your care team. You might want to be extra careful.

Possible Side Effects:

• Rash
• Hypertension
• Diarrhea
• Fatigue
• Nausea
• Vomiting
• Shortness of breath
• Bone pain
• Anemia
• Loss of appetite
• Sweating
• Bone thinning
• Cough

Safety Advise:

🫀 Liver

Letrozole can damage the liver and increase liver enzymes. Routine liver function tests are advised, especially for those with existing liver disease. Please speak to your healthcare provider.

🫘 Kidney

It is recommended that people, especially those with kidney disease, should have their kidney function tested regularly. Please talk to your health care provider.

🤰 Pregnancy

Letrozole can cause harm to an unborn child. Effective contraception should be used during the treatment. Please talk to your healthcare provider.

🤱 Breast feeding

Breastfeeding is generally not advised during treatment as the excretion of letrozole into the breast milk is not known. Please consult your health care professional.

🍺 Alcohol

The safety of combining Letall 2.5mg Tablet with alcohol is not known. Talk to your doctor.

Storage Instructions:

Keep in a dry place at room temperature (15°C to 30°C) away from light and moisture.

References

• Novartis Pharmaceuticals Corporation. FEMARA (Letrozole) Tablets: Highlights of Prescribing Information. U.S. Food and Drug Administration.
• Goss PE, Ingle JN, Martino S, et al. A Randomized Trial of Letrozole in Postmenopausal Women after Five Years of Tamoxifen Therapy for Early-Stage Breast Cancer. New England Journal of Medicine. 2003;349(19):1793-1802.
• Mouridsen H, Gershanovich M, Sun Y, et al. Phase III Study of Letrozole versus Tamoxifen as First-Line Therapy of Advanced Breast Cancer in Postmenopausal Women. Journal of Clinical Oncology. 2001;19(10):2596-2606.
• Brunton LL, Knollmann BC, eds. Goodman & Gilman’s The Pharmacological Basis of Therapeutics. 14th ed. New York: McGraw-Hill Education.
• Tripathi KD. Essentials of Medical Pharmacology. 8th ed. New Delhi: Jaypee Brothers Medical Publishers.

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Manufacturer details

Name: Intas Pharmaceuticals Ltd

Address: Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad – 380009. Gujarat. India.

Country of origin: India