Cipcza 2.5gm Injection

Cipcza 2.5gm Injection contains Ceftazidime, Avibactam, An antibiotic injection is used to treat serious bacterial infections of the stomach, urinary system and lungs. It can be used to treat a variety of illnesses in both adults and children, either alone or combined with other antibiotics like metronidazole.

Uses of Cipcza 2.5gm Injection:

• Urinary tract infections
• Intra-abdominal infections
• Hospital-acquired bacterial pneumonia and ventilator-associated bacterial pneumonia.

How does Cipcza 2.5gm Injection work?

Ceftazidime is a third-generation cephalosporin antibiotic that stops the bacterial cell wall from forming, killing the cell by lysis. Avibactam is a non-beta-lactam beta-lactamase inhibitor that protects ceftazidime against degradation by certain enzymes produced by resistant bacteria thus restoring the activity of ceftazidime against beta-lactamase producing infections.

How to Use & Dosage

Given intravenously, usually over a period of 2 hours. Dosage and duration are dependent on the type and severity of the infection and on patient factors such as renal function.

This drug is given by injection into a vein or muscle every 8 to 12 hours. The dose for children is calculated according to body weight and medical condition. Check the product visually for particles or discoloration before use. Ask your health care provider how to prepare and store it properly. If a pre-mixed solution has been frozen, allow it to thaw at room temperature or in a refrigerator and shake well before using. The best way to take the antibiotic is to take it at equal intervals.

Possible Side Effects:

• Fatigue
• Hot flashes
• Hypertension
• Nausea
• Vomiting
• Allergic reactions (anaphylaxis)
• Renal impairment
• Seizures

Safety Advise:

🩺 Kidney

Cipcza 2.5gm injection can be safely used in patients with renal disease. Take Cipcza 2.5gm injection as prescribed by your doctor.

🤰 Pregnancy

Consuming a 2.5gm injection of Cipcza while pregnant is exceedingly risky. Consult your physician; research in pregnant women and animals has shown significant risks to the developing infant.

🤱 Breastfeeding

Cipcza 2.5gm injection is not safe while you are breast feeding. Data indicate that the medicine may be dangerous to the baby.

Storage Instructions

Store in a cool, dry place, away from direct sunlight. Follow the specific storage instructions after reconstitution as indicated in the product literature.

References:

1. AVYCAZ® (ceftazidime and avibactam) for Injection, for Intravenous Use. Full Prescribing Information. Silver Spring, MD: U.S. Food and Drug Administration.
2. Sharma R, Eun Park T, Moy S. Ceftazidime-Avibactam (Avycaz): For the Treatment of Complicated Intra-Abdominal and Urinary Tract Infections. Pharmacy and Therapeutics. 2016;41(1):11-14.
3. Wagenlehner FM, Sobel JD, Newell P, et al. Ceftazidime-Avibactam Versus Doripenem for the Treatment of Complicated Urinary Tract Infections, Including Acute Pyelonephritis: RECAPTURE, a Phase 3 Randomized Trial Program. Clinical Infectious Diseases. 2016;63(6):754-762.
4. Torres A, Zhong N, Pachl J, et al. Ceftazidime-Avibactam Versus Meropenem in Nosocomial Pneumonia, Including Ventilator-Associated Pneumonia (REPROVE): A Randomised, Double-Blind, Phase 3 Non-Inferiority Trial. The Lancet Infectious Diseases. 2018;18(3):285-295.
5. Brunton LL, Knollmann BC, eds. Goodman & Gilman’s The Pharmacological Basis of Therapeutics. 14th ed. New York: McGraw-Hill Education.

Disclaimer:

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Manufacturer details

Name: Cipla Ltd

Address: Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013

Country of origin: India