Difidox 100mg Injection

Difidox 100mg Injection contains Doxycycline, a broad spectrum tetracycline antibiotic. It is often used to treat a number of bacterial infections including those caused by susceptible bacteria, skin infections, respiratory tract infections and STDs.

Uses of Difidox 100mg Injection:

• Respiratory tract infections
• Urinary tract infections
• Skin and soft tissue infections
• Certain sexually transmitted infections
• Rickettsial infections
• Malaria prophylaxis
• the hospital.

How does Difidox 100mg Injection work?

Doxycycline is an antibiotic belonging to the tetracycline class that prevents bacteria from synthesizing proteins. It binds to the bacterial 30S ribosomal subunit and prevents aminoacyl-tRNA joining the mRNA-ribosome complex. This stops bacterial growth by preventing amino acids from being added to the growing peptide chain (bacteriostatic action).

How to Use & Dosage

Given by intravenous (IV) infusion; usually it is diluted and given over a period of one to four hours. Dosage and length of time depend on the type and severity of the infection.

Doxycycline is administered as an injection, in the form of a powder, which is mixed with a liquid and given intravenously (into a vein). It is usually administered every twelve or twenty-four hours over a period of one to four hours. Your course of treatment will depend on your type of illness and how your body responds to the medicine.

You can take this drug at home, or have an injection of doxycycline in hospital. If you will be getting doxycycline injections at home, your healthcare professional will show you how to use the drug. Please be sure you understand these instructions, and if you have any questions, call your healthcare practitioner.

Possible Side Effects:

• Nausea
• Vomiting
• Diarrhea
• Abdominal pain
• Loss of appetite
• Rash
• Dry mouth
• Esophagitis

Safety Advise:

🫁 Lungs

The safety of Difidox Injection in people with lung problems is not known. Please talk to your healthcare provider.

🫀 Liver

The safety of Difidox Injection in persons with liver disease has not been established. Talk to your health care provider.

🩺 Kidney

It is not known if Difidox Injection is safe in people with kidney problems. Consult your doctor.

🤰 Pregnancy

Difidox should only be used during pregnancy if clearly needed. Please speak to your healthcare provider.

🤱 Breast Feeding

Using Difidox while nursing is most likely dangerous. Talk to your doctor.

Storage Instructions

Store below 25°C, protect from direct sunlight. Keep out of children’s reach.

References

1. Cunha BA, Sibley CM, Ristuccia AM. Doxycycline. Therapeutic Drug Monitoring. 1982 Jun 1;4(2):115.
2. Blanchard P, Rudhardt M, Fabre J. Behaviour of doxycycline in the tissues. Chemotherapy. 1975 Jan 1;21(Suppl 1):8-18.
3. Abd El-Aty AM, Goudah A, Zhou HH. Pharmacokinetics of doxycycline after administration as a single intravenous bolus and intramuscular doses to non-lactating Egyptian goats. Pharmacological Research. 2004 May 1;49(5):487-91.
4. Majewski M. A current opinion on the safety and efficacy of doxycycline including parenteral administration–A review. Polish Annals of Medicine. 2014 Jun 1;21(1):57-62.

Disclaimer:

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