Evermil 5mg Tablet

Evermil 5mg Tablet contains Everolimus as an active ingredient and it belongs to the group of mTOR inhibitors (mammalian target of rapamycin inhibitors). It is mostly used for the treatment of cancer and other diseases.

Uses of Evermil 5mg Tablet

• Renal Cell Carcinoma
• Tumours of the pancreatic neuroendocrine type
• Hormone-receptor positive breast cancer
• Tuberous Sclerosis Complex (TSC)

How does the Evermil 5mg Tablet work?

Everolimus inhibits a critical pathway (mTOR) which is involved in cell growth, division and survival. Everolimus inhibits mTOR, which slows cell division and limits the growth of cancerous cells.

How to Use & Dosage

The typical dosage is 5mg once daily, but it can vary based on the specific condition being treated and the patient’s response. Taken orally, with or without food. It is important to take it consistently at the same time each day.

Follow all of the instructions given to you by your doctor or pharmacist. Do not drink grapefruit juice. Do not break, crush or chew the tablets. Take them at the same time each day and at regular intervals and do not stop unless your doctor tells you to. Your pharmacist will give you a MedGuide with every prescription and refill. Always read the information carefully.

Discuss with your paediatrician the use of this medicine in children. Precautions apply, although this medication may be given for some diseases in children as young as one year old.

Consult your paediatrician for the use of this medication in young patients. Precautions do apply, but this medication may be used for some diseases in children as young as one year old.

Possible Side Effects

• Mouth sores
• Nausea
• Diarrhea
• Fatigue
• Rash
• Fever
• Loss of appetite
• Increased risk of infections due to immunosuppression
• Pneumonitis
• Elevated cholesterol and triglycerides

Safety Advise

🩺 Kidney

Everolimus may be associated with an increase in creatinine levels, which may be indicative of renal impairment. Patients should have routine renal function testing while receiving treatment. Please talk to your Healthcare Provider.

⚠️ Liver

Evermil 5 Tablet is not recommended for use in patients with severe liver disease. Please consult your Healthcare Provider.

🤰 Pregnancy

Everolimus may cause foetal harm when administered to a pregnant woman, resulting in foetal death or birth defects. Please speak with your Healthcare Provider.

🤱 Breastfeeding

Everolimus should not be used by women who are breastfeeding as it could be passed into breast milk and could cause harm to a baby who is being nursed. Please talk to your Healthcare Provider.

🍷 Alcohol

The effect of alcohol on Evermil 5 Tablet is unknown. Please consult your doctor before consuming alcohol. Please talk to your Healthcare Provider.

🚗 Driving

Some patients may have fatigue or dizziness. Drive carefully until you know how Everolimus affects you.

Storage Instructions

Store at room temperature. Keep away from moisture and heat. Keep out of the reach of children.

References

• Tripathi KD. Essentials of Medical Pharmacology. 8th ed. New Delhi: Jaypee Brothers Medical Publishers.
• Katzung BG, Vanderah TW. Basic and Clinical Pharmacology. 15th ed. New York: McGraw Hill.
• Novartis Pharmaceuticals Corporation. Afinitor (Everolimus) Tablets Prescribing Information. U.S. Food and Drug Administration.
• Motzer RJ, Escudier B, Oudard S, et al. Efficacy of Everolimus in advanced renal cell carcinoma: a double-blind, randomised, placebo-controlled phase III trial. The Lancet. 2008;372(9637):449-456.
• Baselga J, Campone M, Piccart M, et al. Everolimus in postmenopausal hormone-receptor-positive advanced breast cancer. New England Journal of Medicine. 2012;366(6):520-529.

Disclaimer

IHS Enterprises’s primary objective is to guarantee the accuracy, reliability, and specialist review of the information it provides to customers. The contents and information provided on this website are for informational purposes only. They should not be used as a substitute for professional medical advice, diagnosis, or treatment. Always consult your physician for guidance and any questions you may have about any condition or medication. If you do read anything from IHS Enterprises, please do not discount or delay in seeking competent medical advice. We want to enhance the doctor-patient relationship, not substitute it.

Manufacturer Details

Name: Glenmark Pharmaceuticals Ltd

Address: Glenmark Pharmaceuticals Limited, B/2, Mahalaxmi Chambers, 22, Bhulabhai Desai Road, Mumbai – 400 026.

Country of Origin: India