Kaviox 500mg Injection

Kaviox 500mg Injection is an antibiotic injection which contains Avibactam, used to treat serious bacterial infections of the stomach, urinary system and lungs. It is used to treat a range of illnesses in both adults and children and can be used alone or in combination with other antibiotics such as Ceftazidime.

Uses of Kaviox 500mg Injection:

• Urinary tract infections
• Intra-abdominal infections
• Hospital-acquired bacterial pneumonia and ventilator-associated bacterial pneumonia.

How does Kaviox 500mg Injection work?

The non-β-lactam β-lactamase inhibitor avibactam protects certain β-lactam antibiotics from enzymatic degradation. It acts by reversibly binding to the serine residue in the active site of β-lactamases, in particular those that are class A (KPC carbapenemases), class C (AmpC enzymes), and some class D enzymes (OXA-48). Avibactam inhibits these enzymes, preventing the hydrolysis of these drugs, thus restoring and boosting the antibacterial activity of antibiotics such as ceftazidime against resistant Gram-negative bacteria.

How to Use & Dosage

Usually given intravenously over a period of 2 hours. Dosage and length of treatment depend on the type and severity of the infection and on patient factors such as renal function.

It is injected into a vein or muscle every 8 to 12 hours. The dose for children depends on their weight and medical condition. Check for particles or discoloration before use. Ask your healthcare provider how to properly prepare and store it. When using a frozen pre-mixed solution, thaw it at room temperature or in the refrigerator and give it a good shake. To get the most benefit, give the antibiotic at even intervals.

Possible Side Effects:

• Fatigue
• Hot flashes
• Hypertension
• Nausea
• Vomiting
• Allergic reactions (anaphylaxis)
• Renal impairment
• Seizures

Safety Advise:

🩺 Kidney

Kaviox injection can be safely used in patients with renal disease. Use Kaviox injection exactly as directed.

🤰 Pregnancy

Kaviox injection is very dangerous to take when pregnant. Talk to your doctor; studies on pregnant women and animals have shown significant risk to the developing infant.

🤱 Breast-Feeding

Kaviox injection should not be used during breast feeding. The data suggest that the drug may be harmful to the infant.

Storage Instructions

Keep out of direct sunlight and in a cool, dry location. As stated in the product literature, adhere to the particular storage instructions after reconstitution.

References

1. Ehmann DE, Jahić H, Ross PL, Gu RF, Hu J, Kern G, Walkup GK, Fisher SL. Avibactam is a covalent, reversible, non–β-lactam β-lactamase inhibitor. Proceedings of the National Academy of Sciences. 2012 Jul 17;109(29):11663-8.
2. Herrero FS. Ceftazidime-avibactam. Revista Española de Quimioterapia. 2022 Apr 22;35(Suppl 1):40.
3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 51.

Disclaimer:

IHS Enterprises’s primary objective is to guarantee the accuracy, reliability, and specialist review of the information it provides to customers. The contents and information provided on this website are for informational purposes only. They should not be used as a substitute for professional medical advice, diagnosis, or treatment. Always consult your physician for guidance and any questions you may have about any condition or medication. If you do read anything from IHS Enterprises, please do not discount or delay in seeking competent medical advice. We want to enhance the doctor-patient relationship, not substitute it.

Manufacturer details

Name: Fusion Healthcare Pvt Ltd

Address: Fusion House, Plot No. 22, H.No 8-2-350/B, Road No. 3, Banjara Hills, Hyderabad, Telangana-500034

Country of origin: India