Lenalid 25mg Capsule

Lenalid 25mg Capsule is an immunomodulatory drug. It is used for the treatment of multiple myeloma and some other types of cancer. It works by modifying the immune system, blocking cancer cells from growing, and blocking the growth of blood vessels that cancers need to grow. It is related to thalidomide.

Uses of Lenalid 25mg Capsule

• Multiple Myeloma
• Myelodysplastic Syndromes
• Mantle Cell Lymphoma

How does the Lenalid 25mg Capsule work?

Lenalidomide modulates the immune response to cancer cells and inhibits angiogenesis (the formation of new blood vessels) and has a direct anti-tumour effect. It also stimulates the activity of natural killer cells and T cells, leading to destruction of abnormal cells.

How to Use & Dosage

Lenalidomide modulates the immune response to cancer cells and inhibits angiogenesis (the formation of new blood vessels) and has a direct anti-tumour effect. It also stimulates the activity of natural killer cells and T cells, leading to destruction of abnormal cells.

Take lenalidomide by mouth once daily, with or without food, as directed by your doctor. Take exactly as prescribed. Ask your doctor or pharmacist if you have any questions.

Swallow the capsules whole with plenty of water. Do not chew, crack or open the capsules. Avoid handling the capsules too much. If you come into contact with a broken lenalidomide capsule or the medicine inside, wash the affected part of your body with soap and water. If the medicine in the capsule gets on your mouth, nose or eyes, wash them well with water.

Possible Side Effects

• Rash
• Hypertension
• Diarrhea
• Fatigue
• Nausea
• Vomiting
• Shortness of breath
• Bone pain
• Anemia
• Loss of appetite
• Dry skin
• Cough

Safety Advise

🫀 Liver

Lenalidomide can damage the liver and increase liver enzymes. Regular liver function tests are recommended, especially for those with existing liver disease. Kindly speak with your doctor.

🫘 Kidney

It is recommended for people, especially those who have kidney disease, to have their kidney function tested on a regular basis. Kindly speak with your healthcare provider.

🤰 Pregnancy

Lenalidomide may cause harm to your developing fetus. Effective contraception should be used throughout treatment. Check with your doctor.

🤱 Breast Feeding

Whether Lenalidomide is excreted in breast milk is not known and breastfeeding is therefore generally not recommended during treatment with this drug. Please consult your physician.

🍺 Alcohol

It is not known if it is safe to use Lenalid 25mg Capsule with alcohol. Please speak to your healthcare provider.

Storage Instructions

Store at room temperature 15°C to 30°C in a dry place, protected from light and moisture.

References

• Kotla V, Goel S, Nischal S, Heuck C, Vivek K, Das B, Verma A. Mechanism of action of lenalidomide in hematological malignancies. Journal of Hematology & Oncology. 2009;2:1-10.
• Chanan-Khan AA, Cheson BD. Lenalidomide for the treatment of B-cell malignancies. Journal of Clinical Oncology. 2008 Mar 20;26(9):1544-52.
• Armoiry X, Aulagner G, Facon T. Lenalidomide in the treatment of multiple myeloma: a review. Journal of Clinical Pharmacy and Therapeutics. 2008 Jun;33(3):219-26.
• Chen N, Zhou S, Palmisano M. Clinical pharmacokinetics and pharmacodynamics of lenalidomide. Clinical Pharmacokinetics. 2017 Feb;56:139-52.
• Gribben JG, Fowler N, Morschhauser F. Mechanisms of action of lenalidomide in B-cell non-Hodgkin lymphoma. Journal of Clinical Oncology. 2015 Sep 1;33(25):2803-11.

Manufacturer Details

Name: Natco Pharma Ltd

Address: Natco House, Road No. 2, Banjara Hills, Hyderabad – 500034, India

Country of origin: India