Pomalid 1mg Capsule

Pomalid 1mg Capsule is a capsule that contains Pomalidomide. It is an immunomodulatory drug, mostly used for the treatment of multiple myeloma, a kind of blood cancer. It is generally given to people who have had their disease progress after treatment with other drugs, including proteasome inhibitors and lenalidomide.

Uses of Pomalid 1mg Capsule:

• Multiple Myeloma

How does a Pomalid 1mg Capsule work?

Pomalidomide works in a complicated way, by stimulating the immune system and also by acting directly against the cancer. It boosts the immune response of the body against cancer cells by activating T-cells and natural killer cells. It also stops multiple myeloma cells growing and causes apoptosis by blocking critical signaling pathways which promote cancer cell growth. It also inhibits angiogenesis, which reduces the blood supply to the tumor, needed for its growth.

How to Use & Dosage

Pomalid 1 mg The dose of capsules can be titrated based on renal function, adverse events and patient tolerance. Swallow the capsules whole with water. Do not chew, crush or open the capsules.

Follow your doctor’s instructions on how to take this drug by mouth with or without food one time each day for 21 days followed by a 7 day break. This is one cycle of therapy. Continue taking the medication as directed by your physician.

Swallow the capsules whole with a glass of water. The capsules should not be opened, broken, crushed, chewed, or handled more than necessary. If any powder from the capsule gets on your skin, wash the area with soap and water.

Possible Side Effects:

• Nausea
• Vomiting
• Diarrhea
• Rash
• Headache
• Weakness
• Fever
• Anemia
• Neutropenia
• Difficulty breathing
• Allergic reactions
• Mouth sores
• Constipation

Safety Advise:

🫀 Liver

Paclitaxel may cause elevated liver enzymes and liver function tests should be monitored during long-term treatment in patients with liver disease. Speak with your doctor or other health professional.

🫘 Kidney

Dose adjustment is required in patients with renal impairment. Please speak with your healthcare provider.

🤰 Pregnancy

Use pomalidomide during pregnancy only when clearly needed and under medical supervision. The safety of pomalidomide during pregnancy has not been established. Please talk to your health care provider.

🤱 Breast Feeding

Be careful while breast-feeding. The drug can get into breast milk. Check with your health care provider.

🍺 Alcohol

It is not known if it is safe to drink alcohol with a Pomalid 1mg capsule. Be sure to discuss this with your doctor.

Storage Instructions:

Store below 25 degrees C. Protect from light and moisture. Keep away from children.

References

• Bristol-Myers Squibb Company. POMALYST (Pomalidomide) Capsules: Highlights of Prescribing Information, Including Boxed Warning. U.S. Food and Drug Administration.
• San Miguel J, Weisel K, Moreau P, et al. Pomalidomide Plus Low-Dose Dexamethasone versus High-Dose Dexamethasone Alone for Patients with Relapsed and Refractory Multiple Myeloma. The Lancet Oncology. 2013;14(11):1055-1066.
• Richardson PG, Siegel DS, Vij R, et al. Pomalidomide Alone or in Combination with Low-Dose Dexamethasone in Relapsed and Refractory Multiple Myeloma. Blood. 2014;123(12):1826-1832.
• Brunton LL, Knollmann BC, eds. Goodman & Gilman’s The Pharmacological Basis of Therapeutics. 14th ed. New York: McGraw-Hill Education.
• Tripathi KD. Essentials of Medical Pharmacology. 8th ed. New Delhi: Jaypee Brothers Medical Publishers.

Disclaimer:

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Manufacturer details

Name: Natco Pharma Ltd

Address: Natco House, Road No.2, Banjara Hills, Hyderabad-500 034, India

Country of origin: India