Soranib 200mg Tablet 30’s

Soranib 200mg Tablet contains Sorafenib, a tyrosine kinase inhibitor used in the treatment of liver, kidney, and thyroid cancers.

Uses of Soranib 200mg Tablet 30’s

• Renal Cancer
• Liver Cancer
• Thyroid Cancer

How does the Soranib 200mg Tablet 30’s work?

Sorafenib is a multi-kinase inhibitor that targets receptor tyrosine kinases involved in tumour angiogenesis and tumour growth. It mainly inhibits:

• Vascular Endothelial Growth Factor Receptor (VEGFR)
• Platelet-Derived Growth Factor Receptor (PDGFR)
• Raf kinase, a component of the MAPK/ERK signalling pathway

By blocking these pathways, Sorafenib helps prevent tumour growth, reduces the formation of new blood vessels (angiogenesis), and promotes programmed cell death (apoptosis) in cancer cells.

How to Use & Dosage

The usual recommended dose of Soranib 200mg Tablet is 400 mg twice daily. Your doctor may adjust the dose depending on your response to treatment and how well you tolerate the medicine.

Take the tablet on an empty stomach, at least 1 hour before or 2 hours after meals. Swallow the tablet whole with water. Do not crush, chew, or break it.

If this medicine is prescribed for children, consult your healthcare provider and follow the prescribed instructions carefully. Take the medicine regularly as directed. If you suspect an overdose, seek emergency medical attention or contact a poison control center immediately.

Possible Side Effects

• Diarrhea
• Fatigue
• Nausea
• Vomiting
• Skin rash or dermatitis
• Hand-foot syndrome
• Hypertension
• Gastrointestinal bleeding
• Heart failure

Safety Advice

🫁 Lungs

Soranib 200mg Tablet should be used with caution in patients with certain lung conditions. Please consult your healthcare provider.

⚠️ Liver

Use Soranib 200mg Tablet with caution in patients with severe liver disease. Dose adjustments may be required. Please discuss this with your healthcare provider.

🤰 Pregnancy

Soranib 200mg Tablet should not be used during pregnancy as it may cause harm to the developing fetus. Please consult your healthcare provider.

🤱 Breastfeeding

Breastfeeding is not recommended while taking Soranib 200mg Tablet, as the medicine may pass into breast milk and could harm a nursing infant. Please consult your healthcare provider.

🍺 Alcohol

It is not known whether it is safe to consume alcohol while taking Soranib 200mg Tablet. Please discuss this with your healthcare provider.

Storage Instructions

Store at room temperature (20°C to 25°C) in a dry place away from moisture. Keep the tablets in their original packaging, protect them from direct sunlight, and keep out of the reach of children.

References

• Llovet JM, et al. Sorafenib in Advanced Hepatocellular Carcinoma. N Engl J Med. 2008;359(4):378-390.
• Escudier B, et al. Sorafenib in Advanced Clear-Cell Renal-Cell Carcinoma. N Engl J Med. 2007;356(2):125-134.
• Brose MS, et al. Sorafenib in Radioactive Iodine-Refractory, Locally Advanced or Metastatic Differentiated Thyroid Cancer: A Randomised, Double-Blind, Phase 3 Trial. Lancet. 2014;384(9940):319-328.
• NEXAVAR (Sorafenib) Prescribing Information. U.S. FDA.

Disclaimer

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