Tipanat 20mg Tablet

Tipanat 20mg Tablet is primarily used to treat advanced or metastatic colorectal cancer, particularly when other medications have not been effective.

Uses of Tipanat 20mg Tablet:

• Colorectal Cancer

How does a Tipanat 20mg Tablet work?

Tipiracil and trifluridine have a synergy. Trifluridine works directly on the cancer cells by being incorporated into the DNA of the cells. This incorporation causes damage to the DNA and results in cell death. Tipiracil inhibits the enzyme that degrades trifluridine, thereby increasing and prolonging the activity of trifluridine.

How to Use & Dosage

The usual dosage depends on the body surface area (BSA) and the type of cancer being treated. Take with water within 30 minutes of eating to reduce gastrointestinal adverse effects. Do not chew or break the tablets.

Possible Side Effects:

• Redness
• Swelling
• Diarrhea
• Nausea
• Vomiting
• Fatigue
• Loss of appetite
• Stomatitis (mouth sores)
• Dehydration
• Chest pain
• Severe Hand-Foot Syndrome

Safety Advise:

❤️ Heart

Tipanat should be used with caution in patients with heart disease as it may cause angina or other heart-related problems. Please consult your healthcare provider.

🫘 Kidney

Tipanat should be used with caution in patients with a history of renal impairment, as it may cause other kidney related problems. Please discuss with your healthcare provider.

🫀 Liver

Tipanat should be taken with caution if you have a history of liver disease as it may cause other liver related problems. Please consult with your healthcare provider.

🤰 Pregnancy

Pregnancy Tipanat 20mg Tablets are not recommended in pregnant women as they may harm the fetus. Please consult your healthcare provider.

🤱 Breast Feeding

It is not known whether tipanat 20mg tablet passes into breast milk or if it affects your breast milk. If you are taking this medicine, ask your doctor how to feed your child as healthily as possible.

🍺 Alcohol

It is suggested to stop drinking while using tipanat 20mg Tablet to avoid the unwanted side effects. Please consult your doctor.

🚗 Driving

Tipanat 20mg Tablet may make you feel sleepy or dizzy. do not drive or operate machinery until you know how it affects you. Speak with your healthcare provider.

Storage Instructions:

Store in a cool, dry place, out of direct sunlight and humidity, at room temperature (15-30°C). Keep out of the reach of children.

References

• Burness CB, Duggan ST. Trifluridine/tipiracil: a review in metastatic colorectal cancer. Drugs. 2016 Sep;76:1393-402.
• Peeters M, Cervantes A, Moreno Vera S, Taieb J. Trifluridine/tipiracil: an emerging strategy for the management of gastrointestinal cancers. Future Oncology. 2018 Jul;14(16):1629-45.
• Cuissy S, Sefrioui D. Metastatic colorectal cancer: Trifluridine-tipiracil and bevacizumab. The results of the SUNLIGHT study bring an end to the questioning about whether to use trifluridine-tipiracil or regorafenib. Hépato-Gastro & Oncologie Digestive. 2024;31(2):267-72.
• Jeffers KD. Trifluridine/tipiracil: old drug, new tricks. Journal of the Advanced Practitioner in Oncology. 2016 May;7(4):449.

Disclaimer:

IHS Enterprises’s primary objective is to guarantee the accuracy, reliability, and specialist review of the information it provides to customers. The contents and information provided on this website are for informational purposes only. They should not be used as a substitute for professional medical advice, diagnosis, or treatment. Always consult your physician for guidance and any questions you may have about any condition or medication. If you do read anything from IHS Enterprises, please do not discount or delay in seeking competent medical advice. We want to enhance the doctor-patient relationship, not substitute it.

Manufacturer details

Name: Natco Pharma Ltd

Address: Natco House, Road No.2, Banjara Hills, Hyderabad-500 034, India

Country of origin: India