Xylistin 1 MIU Injection

Xylistin 1 MIU Injection is an antibiotic that contains colistimethate sodium and is used to treat severe bacterial infections caused by multidrug resistant Gram-negative bacteria.

Brand Name: Xylistin

Composition: Colistimethate sodium

Mechanism of Action:

Colistin binds with the lipopolysaccharide (LPS) layer of the Gram-negative bacterial membranes and improves the permeability of the membrane. This leads to the contents of the cell to flow out and the bacteria to die. It has very good activity against multidrug resistant (MDR) Gram-negative bacteria including Pseudomonas aeruginosa, Acinetobacter baumannii and certain Enterobacteriaceae.

Uses:

• Severe Respiratory Infections
• Urinary Tract Infections
• Sepsis/Septicemia
• Intra-abdominal Infections
• Bone and Joint Infections
• Meningitis

Dosage and how to take it:

Dosage is generally based on weight and should be determined by a health care professional. Xylistin is administered by intravenous or intramuscular injection.

Possible Side Effects:

• Dizziness
• Nausea
• Vomiting
• Fever
• Tingling
• Muscle weakness
• Rash
• Itching
• Bronchospasm
• Local Pain at the injection site

Safety Advise:

Allergy

Colistin should not be used in patients with a known hypersensitivity to colistin. Please consult your healthcare provider.

Kidney

Colistin use may lead to nephrotoxicity and renal function should be monitored regularly. In patients with impaired renal function, the dose may need to be adjusted. Talk with your health care professional.

Pregnancy

Xylistin 1MIU Injection is likely unsafe to use during pregnancy. Discuss with your healthcare provider.

Breast Feeding

1MIU inj. of xylistin should not be given to nursing mothers unless really necessary. Please consult your health care provider.

Alcohol

Do not drink alcohol while you are taking this medicine as it can worsen your drowsiness, dizziness or tiredness. Please consult your health care provider.

Storage:

Store below 25°C, away from moisture. Use immediately after reconstitution or store briefly in a refrigerator.

Disclaimer:

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