Bevacirel 400mg Injection

Bevacirel 400mg Injection is a cancer drug which contains Bevacizumab, a monoclonal antibody. It works by blocking angiogenesis (that’s how cancers grow their own blood supply).

Uses of Bevacirel 400mg Injection:

• Metastatic Colorectal Cancer
• Non-Small Cell Lung Cancer
• Breast Cancer
• Glioblastoma
• Ovarian Cancer
• Cervical Cancer

How does a Bevacirel 400mg Injection work?

It attaches itself to a protein called vascular endothelial growth factor (VEGF), which encourages the growth of blood vessels. Bevacizumab binds to VEGF and prevents it from binding to receptors on endothelial cells. This prevents the formation of new blood vessels and also prevents the growth and metastasis of the tumor.

How to Use & Dosage

Dosage may vary depending on the particular malignancy treated and general patient health. Bevacizumab is administered as a slow intravenous infusion and the infusion rate can be adjusted according to the patient’s tolerance.

Bevacizumab injection is a liquid that a healthcare provider slowly injects into a vein. It is usually given once every 2 to 3 weeks. The dose schedule is tailored to your individual condition and response to treatment.

Serious adverse reactions, including infusion reactions, have been reported with injectable products containing bevacizumab. Call your doctor right away if you have any of the following symptoms: headaches, dizziness, chest pain, flushing, itching, rash, hives, chills, shivering, sweating, or shortness of breath. If you experience any of these side effects, or others, your doctor may need to slow the rate of your infusion or delay or stop your treatment.

Possible Side Effects:

• Hypertension
• Fatigue
• Diarrhea
• Nausea
• Vomiting
• Fever
• Dizziness
• Increased risk of bleeding

Safety Advise:

🫀 Liver

Use with caution in patients with hepatic impairment, and dosage adjustments may be necessary. Be sure to talk to your health care provider.

🫘 Kidney

Use with caution in patients with renal impairment and dosage adjustment may be required. Please consult your health care provider.

🤰 Pregnancy

It has not been sufficiently proven safe in pregnancy and should only be used when absolutely necessary. Please discuss with your healthcare provider.

🤱 Breast Feeding

Possibly unsafe to use Bevacirel Injection during breastfeeding. Please discuss with your healthcare provider.

🍺 Alcohol

Do not drink alcohol when using Bevacirel Injection. Please talk to your health care provider.

Storage Instructions:

Store at room temperature, 20° to 25° C. Keep the container tightly closed.

References

1. Kazazi-Hyseni F, Beijnen JH, Schellens JH. Bevacizumab. The oncologist. 2010 Aug;15(8):819.
2. Braghiroli MI, Sabbaga J, Hoff PM. Bevacizumab: overview of the literature. Expert review of anticancer therapy. 2012 May 1;12(5):567-80.
3. Bakri SJ, Snyder MR, Reid JM, Pulido JS, Singh RJ. Pharmacokinetics of intravitreal bevacizumab (Avastin). Ophthalmology. 2007 May 1;114(5):855-9.
4. Keating GM. Bevacizumab: a review of its use in advanced cancer. Drugs. 2014 Oct;74(16):1891-925.

Disclaimer:

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Manufacturer details

Name: Reliance Life Sciences

Address: Dhirubhai Ambani Life Sciences Centre, R-282, TTC Area of MIDC, Thane-Belapur Road, Rabale, Navi Mumbai 400 701

Country of origin: India