Cizumab 100mg Injection

Cizumab 100mg Injection Contains Bevacizumab, a monoclonal antibody that is used for cancer therapy. This blocks the formation of new blood vessels. This is how cancers grow their own blood supply.

Uses of Cizumab 100mg Injection:

• Metastatic Colorectal Cancer
• Non-Small Cell Lung Cancer
• Breast Cancer
• Glioblastoma
• Ovarian Cancer
• Cervical Cancer

How does a Cizumab 100mg Injection work?

It binds to and targets vascular endothelial growth factor (VEGF), a protein that promotes the formation of blood vessels. Bevacizumab binds to VEGF to prevent it from binding to its receptors on endothelial cells. This prevents the growth of new blood vessels and the growth and spread of tumours.

How to Use & Dosage

The dose can differ according to the type of malignancy being treated and the patient’s general health. The rate of infusion of bevacizumab should be adjusted according to the patient’s tolerance. Bevacizumab injection is a liquid that a medical expert gives you by slowly injecting it into a vein once every two to three weeks. The timing of your doses will be decided for you depending on your condition and how you are responding to treatment.

Bevacizumab injectable products can cause serious adverse effects when injected. Inform your doctor at once if you have any of these symptoms: headaches, dizziness, chest pain, flushing, itching, rash, hives, chills, shaking, sweating, shortness of breath. If you have these or other side effects, your doctor may need to slow down your infusion rate or delay or terminate treatment.

Possible Side Effects:

• Hypertension
• Fatigue
• Diarrhea
• Nausea
• Vomiting
• Fever
• Dizziness
• Increased risk of bleeding

Safety Advise:

🫀 Liver

Use with caution in patients with hepatic impairment; may require dosage adjustment. Please consult your healthcare professional.

🫘 Kidney

Caution is advised in patients with renal impairment and dosage adjustment may be necessary. Please discuss with your healthcare provider.

🤰 Pregnancy

Safety during pregnancy has not been well established so it should be used only if clearly needed. Please consult your healthcare provider.

🤱 Breast-feeding

It is not known if Cizumab Injection passes into breast milk. Please discuss with your healthcare provider.

🍺 Alcohol

During treatment with Cizumab Injection, intake of alcohol is not recommended. Please consult your health care provider.

Storage Instructions:

Keep Cizumab Injection away from direct sunlight and store at room temperature, 20°C to 25°C.

References

1. Burness CB, Duggan ST. Trifluridine/tipiracil: a review in metastatic colorectal cancer. Drugs. 2016 Sep;76:1393-402.
2. Peeters M, Cervantes A, Moreno Vera S, Taieb J. Trifluridine/tipiracil: an emerging strategy for the management of gastrointestinal cancers. Future Oncology. 2018 Jul;14(16):1629-45.
3. Cuissy S, Sefrioui D. Metastatic colorectal cancer: Trifluridine-tipiracil and bevacizumab. The results of the SUNLIGHT study bring an end to the questioning about whether to use trifluridine-tipiracil or regorafenib. Hépato-Gastro & Oncologie Digestive. 2024;31(2):267-72.
4. Jeffers KD. Trifluridine/tipiracil: old drug, new tricks. Journal of the Advanced Practitioner in Oncology. 2016 May;7(4):449.

Disclaimer:

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Manufacturer details

Name: Hetero Drugs Ltd

Address: 7-2-A2, Hetero Corporate, Industrial Estates, Sanath Nagar, Hyderabad – 500 018, Telangana, INDIA

Country of origin: India