Siromus 1mg Tablet
₹480.00Current price is: ₹480.00. Original price was: ₹994.69.
Brand Name:Siromus
Category: Transplant
Manufacturer: Zydus Life sciences
Composition: Sirolimus
Minimum Order Quantity: 5
6 Tablet(s) In a Strip
Siromus 1mg Tablet is an immunosuppressive drug used primarily in transplant patients to prevent rejection of the organ and for the treatment of some conditions of the immune system.
Before using this drug inform your doctor if you have any other medical condition or if you are already taking any medicines. You should also tell them if you are pregnant or nursing. Laboratory testing may be recommended by your doctor during therapy, and you should see a doctor immediately if you experience any new growths, changes in moles, signs of infection or unusual tiredness.
Product Description
Siromus 1mg Tablet is an immunosuppressive drug used primarily in transplant patients to prevent rejection of the organ and for the treatment of some conditions of the immune system.
Uses of Siromus 1mg Tablet: Organ Transplant
How does Siromus 1mg Tablet work?
Sirolimus prevents T-lymphocytes from being activated and multiplying in response to antigen and cytokine stimulation. Sirolimus prevents the mammalian target of rapamycin (mTOR) from functioning, and mTOR is a key regulator of cell growth and metabolism.
How to Use & Dosage?
For kidney transplantation, a loading dose of usually 6 mg on the day of transplantation followed by a maintenance dose of 2 mg once daily may be administered. Siromus oral tablets may be taken with or without meals. Consistency is king when it comes to meals.
Take this medication by mouth with no more than 4 ounces of plain water at the same time each day, right after waking up, as directed by your doctor. Swallow the tablets whole and do not eat or drink or take any other drugs for at least half an hour.
Each time you fill a prescription or refill, the pharmacist will give you a unique MedGuide. Read this information carefully every time.Talk to your care team about the use of this drug in children. You should take extra care.
Possible Side Effects:
- Headache
- Nausea
- Fever
- Vomiting
- Joint Pain
- Abdominal pain
- Constipation
- Chills
- Cough
- High Blood Pressure
- Dizziness
- Weight Loss
- Insomnia
Safety Advise:
Liver
Siromus should be used with caution in patients with liver disease. Dose adjustments for siromus may be necessary. Please speak with your healthcare provider.
Kidney
Siromus should be used cautiously in patients with renal illness. Siromus dose adjustments may be needed. Please consult your health care provider.
Pregnancy
Siromus may harm the foetus, based on animal studies. It may not be safe to use during pregnancy. Discuss benefits and risks with your health care provider before use.
Breast Feeding
It is probably unsafe to take Siromus while breastfeeding. Limited human data indicate that the medication may cause harm to the developing baby if it passes into the breastmilk. Please consult your doctor.
Alcohol
It is not known if it is safe to take Siromus with alcohol. Consult your doctor.
Storage Instructions:
Store at 20-25°C (68-77°F) in a tightly closed container, protected from light and moisture.
References:
- Sehgal SN. Sirolimus: its discovery, biological properties, and mechanism of action. InTransplantation proceedings 2003 May 1 (Vol. 35, No. 3, pp. S7-S14). Elsevier.
- Stallone G, Infante B, Grandaliano G, Gesualdo L. Management of side effects of sirolimus therapy. Transplantation. 2009 Apr 27;87(8S):S23-6.
- Stenton SB, Partovi N, Ensom MH. Sirolimus: the evidence for clinical pharmacokinetic monitoring. Clinical pharmacokinetics. 2005 Aug;44:769-86.
- Mahalati K, Kahan BD. Clinical pharmacokinetics of sirolimus. Clinical pharmacokinetics. 2001 Aug;40:573-85.
Manufacturer Details:
Name: Zydus Life Sciences
Address: Zydus Tower, Satellite Cross Roads,Ahmedabad – 380015 Gujarat, India.
Country of origin: India
Frequently Asked Questions (FAQs):
1) What is Siromus 1mg Tablet used for?
It is used to prevent organ rejection after kidney transplantation and in some immune related conditions.
2) What is the price of the Siromus 1 mg Tablet?
In India the price is generally between ₹400 and ₹900 depending on discounts and pharmacy availability.
3) Is Siromus safe for long-term use?
Yes, it is common to be prescribed for long-term immunosuppressive therapy post transplant.
4) How does Siromus work?
It suppresses the immune system in order to allow the body to accept the transplanted organ
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