Merofit 1gm Injection

Merofit 1gm Injection contains Meropenem which is a broad spectrum carbapenem antibiotic used in the treatment of severe bacterial infections. It is very active against a broad spectrum of Gram-positive and Gram-negative bacteria, including strains resistant to other antibiotics.

Uses of Merofit 1gm Injection:

• Pneumonia
• Peritonitis
• Appendicitis
• Urinary Tract Infections
• Septicemia (Blood Infections)
• Skin and Soft Tissue Infections
• Meningitis
• Febrile Neutropenia

How does Merofit 1gm Injection work?

Meropenem acts by binding to penicillin-binding proteins (PBPs) and inhibiting the synthesis of bacterial cell walls. This breaks the cross-linking between the layers of peptidoglycan and weakens the structure of the cell wall. The integrity of the cell wall is compromised thus the bacterial cell is liable to osmotic pressure changes resulting in cell lysis and death. Meropenem is active against a broad range of bacteria including gram-positive and gram-negative bacteria. Its activity against resistant strains is improved by its resistance to many beta-lactamases.

How to Use & Dosage

Administer IV by slow infusion over 15 to 30 minutes or as a bolus injection over approximately 5 minutes.

Meropenem is given as an injection into a vein every 8 hours. The length of treatment depends on your infection and how you respond. Once you start to feel better, your doctor may change you to an oral antibiotic to finish the treatment.

During the first several days of treatment with meropenem injection you should begin to feel better. Contact your doctor if your symptoms get worse or do not get better.

Even if you start to feel better, keep using the meropenem injection until you have taken the whole prescription. If you do not complete the full course of treatment with meropenem injections or miss doses, your infection may not be cured and the bacteria may become resistant to the antibiotics.

Possible Side Effects:

• Nausea
• Vomiting
• Diarrhea
• Rash
• Headache
• Injection site reactions like pain, swelling, or redness.
• Seizures
• Anaphylaxis
• Clostridium difficile-associated diarrhea

Safety Advise:

🫀 Liver

Monitoring of liver enzymes should be performed periodically during therapy, especially in those with underlying hepatic disorders. Talk to your health care provider.

🩺 Kidney

Monitoring of renal function during treatment is important particularly in patients with pre-existing renal disease. Speak with your doctor.

🤰 Pregnancy

Before beginning the Merofit 1gm injection medication, let your healthcare provider know if you are pregnant.

🤱 Breastfeeding

Merofit is eliminated in human milk and it is very dangerous to take a 1g injection of Merofit while breastfeeding. Talk to your health care provider.

🍷 Alcohol

It’s unclear how alcohol consumption and Merofit 1gm injectable interact. Please talk to your doctor about this.

Storage Instructions

Store at 30°C (86°F) or below. Use reconstituted solutions immediately. However, if necessary, they may be stored at 2-8°C for up to 24 hours.

References

1. MERREM® IV (meropenem for injection). Full Prescribing Information. Wilmington, DE: AstraZeneca Pharmaceuticals.
2. Sauberan JB, Bradley JS, Blumer J, Stellwagen LM. Transmission of Meropenem in Breast Milk. Pediatric Infectious Disease Journal. 2012;31(8):832-834.
3. Baldwin CM, Lyseng-Williamson KA, Keam SJ. Meropenem: A Review of Its Use in the Treatment of Serious Bacterial Infections. Drugs. 2008;68(6):803-838.
4. Drugs and Lactation Database (LactMed®). Meropenem. Bethesda, MD: National Institute of Child Health and Human Development.
5. Brunton LL, Knollmann BC, eds. Goodman & Gilman’s The Pharmacological Basis of Therapeutics. 14th ed. New York: McGraw-Hill Education.

Disclaimer:

IHS Enterprises’s primary objective is to guarantee the accuracy, reliability, and specialist review of the information it provides to customers. The contents and information provided on this website are for informational purposes only. They should not be used as a substitute for professional medical advice, diagnosis, or treatment. Always consult your physician for guidance and any questions you may have about any condition or medication. If you do read anything from IHS Enterprises, please do not discount or delay in seeking competent medical advice. We want to enhance the doctor-patient relationship, not substitute it.

Manufacturer details

Name: Fusion Healthcare Pvt Ltd

Address: Fusion House, Plot No. 22, H.No 8-2-350/B, Banjara Hills Rd Number 3, Hyderabad, Telangana 500034.

Country of origin: India